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Now showing items 10504-10523 of 24084
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Identification of excipient-protein interaction hotspots using computational approaches
(2016-06-01)Protein formulation development relies on the selection of excipients that inhibit protein-protein interactions preventing aggregation. Empirical strategies involve screening many excipient and buffer combinations using ... -
Identification of fungi in the Gaeumannomycesp-Phialophora complex by RFLPS of PCR-amplified ribosomal DNAs
(1994-02)The polymerase chain reaction (PCR) was used to amplify ribosomal internal transcribed spacer and 5.8S DNA from isolates of Gaeumannomyces graminis, Phialophora graminicola and other root-infecting fungi, isolated mostly ... -
Identification of Gaeumannomyces-Graminis var. tritici and G-graminis var avenae using a DNA probe and nonmolecular methods
(1992-09)Fungi in the Gaeumannomyces-Phialophora complex were compared using a DNA probe and by pathogenicity and other biological tests. Isolates from cereal and grass hosts which were pathogenic on cereals were differentiated as ... -
Identification of genes differentially expressed in sugar beet roots in response to challenge by polymyxa graminis
(American Society of Sugar Beet Technologists, 2005)Representational difference analysis (RDA) was used to identify expressed sequence tags (ESTs) differentially expressed in sugar beet roots in response to challenge by the ‘non-host’ parasite Polymyxa graminis. Sequence ... -
Identification of membrane proteins of human blood platelets with a hydrophobic photolabel
(1984-12-05)A photoactivable glycolipid probe, 12-(4-azido-2-nitrophenoxy)stearoyl[1-14C]glucosamine, was used to label proteins and lipids of platelet membranes. The proteins were analyzed by two-dimensional high-resolution ... -
Identification of metabolites of a substance P (Neurokinin 1 receptor) antagonist in rat hepatocytes and rat plasma
(2002-01-01)[3R,5R,6S]-3-(2-cyclopropyloxy-5-trifluoromethoxyphenyl)-6-phenyl-1-oxa-7 -azaspiro[4.5]decane is a substance P (Neurokinin 1 receptor) antagonist. Substance P antagonists are proven in concept to have excellent potential ... -
Identification of metabolites of a substance P (NK1 receptor) antagonist in rat hepatocytes and rat plasma
(2002-01-01)The metabolism of a substance P (NK1 receptor) antagonist in rat hepatocytes and rat plasma was described. The samples were prepared for analysis by protein precipitation followed by centrifugation. It was shown that the ... -
Identification of new M dwarfs in the solar neighborhood
(2006-08)We present the results from a spectroscopic study of 1080 nearby active M dwarfs, selected by correlating the Two Micron All Sky Survey and ROSAT catalogs. We have derived the spectral types and estimated distances for all ... -
Identification of new psychoactive substances (NPS) using handheld Raman Spectroscopy employing both 785 and 1064 nm laser sources
(2017-04-01)The chemical identification of new psychoactive substances (NPS) in the field is challenging due not only to the plethora of substances available, but also as a result of the chemical complexity of products and the chemical ... -
Identification of new psychoactive substances using Raman spectroscopy: handheld and computational approaches.
(Research and Advances in Psychiatry, 2016-05)At this conference, I gave a presentation on the identification of new psychoactive substances using handheld Raman spectroscopy and chemometrics. -
Identification of New Single Nucleotide Polymorphism-Based Markers for Inter- and Intraspecies Discrimination of Obligate Bacterial Parasites (Pasteuria spp.) of Invertebrates
(2011-09)Protein-encoding and 16S rRNA genes of Pasteuria penetrans populations from a wide range of geographic locations were examined. Most interpopulation single nucleotide polymorphisms (SNPs) were detected in the 16S rRNA gene. ... -
Identification of Novel Psychoactive Substances in Complex Mixtures Using a Design of Experiment Guided Approach and Handheld Raman Spectroscopy
(2018-07-27)The screening of NPS in street samples has been proven to be problematic in recent years due to their fast appearance, the unavailability of adequate reference materials and their complexity. The aim of this project focussed ... -
Identification of Software Bugs by Analyzing Natural Language-Based Requirements Using Optimized Deep Learning Features
(2024-03-26)Software project outcomes heavily depend on natural language requirements, often causing diverse interpretations and issues like ambiguities and incomplete or faulty requirements. Researchers are exploring machine learning ... -
Identification of target amino acids that affect interactions of fungal polygalacturonases and their plant inhibitors
(2000)Plant polygalacturonase inhibitor proteins (PGIPs) bind fungal polygalacturonases (PGs), but inhibition specificities and kinetics vary within and among species. Purified bean PGIP inhibited all fungal PGs we tested, ... -
Identification of the exciting source of Herbig-Haro objects 135 and 136
(1997)We have identified the exciting source of the Herbig-Haro objects HH135 and 136 by near-infrared polarimetric imaging of the associated extensive reflection nebula. The source is situated at the middle of the two Herbig-Haro ... -
Identification of the lipid-binding site of phosphatidylcholine-transfer protein with phosphatidylcholine analogs containing photoactivable carbene precursors
(1983)The lipid binding site of the phosphatidylcholine transfer protein from bovine liver has been investigated by use of phosphatidylcholine analogs which carry a diazirinophenoxy group linked to the ω-carbon of either the ...