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Now showing items 11012-11031 of 24055
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In vitro recording of mesenteric afferent nerve activity in jejunal and colonic segments from rodents
(2016-10-25)Afferent nerves not only convey information concerning normal physiology, but also signal disturbed homeostasis and pathophysiological processes of the different organ systems from the periphery towards the central nervous ... -
In vitro skin absorption and decontamination of sulphur mustard : Comparison of human and pig-ear skin
(2001)The aim of this study was to evaluate the use of an in vitro skin diffusion cell system as a model for assessing decontaminants against the chemical warfare agent sulphur mustard (SM). The in vitro absorption rates of SM ... -
In vitro studies of siderophore production by wild type and rifampicin resistant strains of fluorescent Pseudomonads
(1989-05)Wild type (Rif−) and rifampicin resistant (Rif+) isolates of fluorescent Pseudomonads were grown in King’s B liquid medium in the presence and absence of iron and subcultured every 48 h for 12 days. Growth rates and the ... -
An in vitro study of the diclofenac delivery properties of hyaluronan in human skin
(1999)Previous in vitro studies have indicated that hyaluronan, when compared to buffer controls, effects a controlled and sustained release of diclofenac through the skin by the formation of a reservoir of the drug around the ... -
In vitro study on influence of nano particles of CuO on CA1 pyramidal neurons of rat hippocampus potassium currents
(2008)The effects of nano particles of CuO on voltage-dependent potassium currents were studied in acutely isolated CA1 pyramidal neurons of rat hippocampus using the whole-cell patch-clamp techniques. Nano particles of CuO had ... -
In vitro susceptibility of Clostridium difficile to SMT19969 and comparators, as well as the killing kinetics and post-antibiotic effects of SMT19969 and comparators against C. difficile
(2015-06-01)OBJECTIVES: SMT19969 is a novel antimicrobial under clinical development for the treatment of Clostridium difficile infection (CDI). The objective was to determine the comparative susceptibility of 82 C. difficile clinical ... -
In vitro susceptibility of genotypically distinct and clonal Clostridium difficile strains to oritavancin
(2008)Clostridium difficile infection is a nosocomial disease of increasing importance. First-line treatment is limited to metronidazole or vancomycin. Oritavancin is a lipoglycopeptide with activity against Gram-positive bacteria, ... -
In vitro synthesis of minus-strand RNA by an isolated cereal yellow dwarf virus RNA-dependent RNA polymerase requires VPg and a stem-loop structure at the 3' end of the virus RNA
(2006-11)Cereal yellow dwarf virus (CYDV) RNA has a 5'-terminal genome-linked protein (VPg). We have expressed the VPg region of the CYDV genome in bacteria and used the purified protein (bVPg) to raise an antiserum which was able ... -
In vitro synthesized RNA generated from cDNA clones of both genomic components of Cucurbit yellow stunting disorder virus replicates in cucumber protoplasts.
(2016-06-14)Cucurbit yellow stunting disorder virus (CYSDV), a bipartite whitefly-transmitted virus, constitutes a major threat to commercial cucurbit production worldwide. Here, construction of full-length CYSDV RNA1 and RNA2 cDNA ... -
An in vitro technique for evaluating inhaled nasal delivery systems
(2002)This report describes a novel technique for delivering aerosols to the surface of respiratory epithelial cells cultured tit an air-liquid interface. A model microsphere formulation for nasal delivery was aerosolised using ... -
In vitro toxicity of multi-walled carbon nanotubes in C6 rat glioma cells
(2012-10)The present study aimed to evaluate the potential toxicity and the general mechanism involved in multi-walled carbon nanotubes (MWCNT)-induced cytotoxicity in C6 rat glioma cell line. Two kinds of MWCNT, which were coded ... -
In vitro toxicity of nanosized copper particles in PC12 cells induced by oxidative stress
(2012-06)Recent evidence suggests that some nanomaterials, which are widely used in many fields, have health effects. In order to investigate the cytotoxicity induced by nanosized copper particles (nano-Cu), PC12 cells, which were ... -
In vitro transcription
(Croom Helm, 1987) -
In vitro transcription in plant nuclei
(1988)Isolated plant nuclei can be used for fundamental studies on the transcription apparatus. Total RNA polymerase activity can be measured using plant nuclei, and by using different α-amanitin concentrations in the enzyme ... -
In vitro transcription of CaMV DNA
(1987) -
In vivo decontamination of the nerve agent VX using the domestic swine model
(2012-11)The purpose of this in vivo study was to assess a new, putatively optimised method for mass casualty decontamination ("ORCHIDS protocol") for effectiveness in removing the chemical warfare agent VX from the skin of ... -
In vivo evaluation of novel hyaluronan/chitosan microparticulate delivery systems for the nasal delivery of gentamicin in rabbits
(2002-01)Biodegradable microparticles containing gentamicin were prepared using chitosan hydroglutamate (CH), hyaluronic acid (HA) and a combination Of both polymers by a solvent evaporation method. These formulations were administered ... -
In vivo skin absorption and distribution of the nerve agent VX (O-ethyl-S-[2(diisopropylamino)ethyl] methylphosphonothioate) in the domestic white pig
(2005-07)The purpose of this study was to characterize the skin absorption and distribution of VX (O-ethyl-S-[2 (diisopropylamino)ethyl] methylphosphonothioate) in the domestic pig in order to evaluate the animal as a potential ...