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Comparison of cytotoxicity of Miltefosine and its niosomal form on chick embryo model
(2024-01-30)
Various drugs have been used for the treatment of leishmaniasis, but they often have adverse effects on the body's organs. In this study, we aimed to explore the effects of one type of drug, Miltefosine (MIL), and its ...
Animal Models of Human Disease
(2023-10-31)
The use of animal models of human disease is critical for furthering our understanding of disease mechanisms, for the discovery of novel targets for treatment, and for translational research. This Special Topic entitled ...
MicroRNAs Regulate Ca 2+ Homeostasis in Murine Embryonic Stem Cells
(2023-07-28)
MicroRNAs (miRNAs) are important regulators of embryonic stem cell (ESC) biology, and their study has identified key regulatory mechanisms. To find novel pathways regulated by miRNAs in ESCs, we undertook a bioinformatics ...
Novel systems to study vector-pathogen interactions in malaria
(2023-05-26)
Some parasitic diseases, such as malaria, require two hosts to complete their lifecycle: a human and an insect vector. Although most malaria research has focused on parasite development in the human host, the life cycle ...
Sheathed fixation improves BASHTI technique in an anterior cruciate ligament reconstruction
(2023-03-30)
Bone and Site Hold Tendon Inside (BASHTI) technique is an implant-less surgical methodology used for anterior cruciate ligament (ACL) reconstruction. It has some clinical advantages, such as speeding up the healing process. ...
Effect of the core bone engaged length on the BASHTI fixation strength, an in-vitro study on bovine tendons using identical-density surrogate bones
(2023-03-25)
Background: BASHTI is an implant-less anterior cruciate ligament (ACL) reconstruction technique, which resolves the problems caused by implants such as interference screws. This study aims to investigate the effect of the ...
Early post-operative performance of an anatomically designed hybrid thread interference screw for ACL reconstruction: A comparative study
(2023-03-05)
Although the anterior cruciate ligament (ACL) reconstruction using interference screw is a well-accepted surgical procedure, patients still suffer graft failure in the initial rehabilitation phase. Graft fixation stability ...
The Impact of Semicarbazide Sensitive Amine Oxidase Activity on Rat Aortic Vascular Smooth Muscle Cells
(2023-03-03)
Semicarbazide-sensitive amine oxidase (SSAO) is both a soluble- and membrane-bound transmembrane protein expressed in the vascular endothelial and in smooth muscle cells. In vascular endothelial cells, SSAO contributes to ...
Mapping odorant sensitivities reveals a sparse but structured representation of olfactory chemical space by sensory input to the mouse olfactory bulb
(2022-07-21)
In olfactory systems, convergence of sensory neurons onto glomeruli generates a map of odorant receptor identity. How glomerular maps relate to sensory space remains unclear. We sought to better characterize this relationship ...
Comparison of mechanical properties in interference screw fixation technique and organic anterior cruciate ligament reconstruction method: a biomechanical study
(2021-12-20)
Background Bone and Site Hold Tendon Inside (BASHTI) technique is an organic implant-less technique for anterior cruciate ligament (ACL) reconstruction with some clinical advantages, such as speeding up the healing process, ...