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Now showing items 10999-11018 of 24064
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In the glimpse of an eye : decision making and vision
(International Society for Psychophysics, 2004)Rapid visual search, depending on iconic memory, is a core but controversial psychophysical topic. A key example is the claim by Horowitz & Wolfe (1998a) that ‘visual search has no memory. Their evidence is the effect of ... -
In the line of duty: the emotional wellbeing of midwives
(2018-09-01)The culture and working practices within midwifery settings are key modifiable factors that influence the emotional wellbeing of midwives. As a caring profession, a culture of self-sacrifice still appears to be expected ... -
In the pink: the strange case of Trinity College Dublin
(2004)According to the frontispiece of Taylor’s history of the University of Dublin, published in 1845, the MA hood of Trinity College was once lined with pink.1 However in Gutch’s table of 1858 the MA lining is listed as dark ... -
In times of crisis invest in maturity : results of an assessment in Iceland
(2010)Following the collapse of the banking system in October 2008, Iceland has faced numerous challenges. Major changes are being made to some of the foundations of the society, for instance the banking sector, but questions ... -
In vitro activity of cadazolid against clinically relevant Clostridium difficile isolates and in an in vitro gut model of C. difficile infection
(2013-10-14)Abstract Objectives We investigated the in vitro activity of cadazolid against 100 Clostridium difficile isolates and its efficacy in a simulated human gut model of C. difficile infection (CDI). Methods MICs of cadazolid, ... -
In Vitro and In Vivo Anticancer Activity of a Novel Nano-sized Formulation Based on Self-assembling Polymers Against Pancreatic Cancer
(2010)Purpose: To evaluate the in vitro and in vivo pancreatic anticancer activity of a nano-sized formulation based on novel polyallylamine grafted with 5% mole cholesteryl pendant groups (CH5-PAA). Methods: Insoluble novel ... -
In vitro and in vivo characterisation of a novel peptide delivery system : Amphiphilic polyelectrolyte–salmon calcitonin nanocomplexes
(2010)The cationic peptide, salmon calcitonin (sCT) was complexed with the cationic amphiphilic polyelectrolyte, poly(allyl)amine, grafted with palmitoyl and quaternary ammonium moieties at pH 5.0 and 7.4 to yield particulates ... -
In vitro and in vivo TNFa synthesis modulation by methylguanidine, an uremic catabolyte
(1999)We have investigated whether methylguanidine (MG), an uremic toxin, modulates the expression of the inducible nitric oxide synthase (iNOS) and nitric oxide (NO) release in vitro in LPS-induced J774 macrophages. -
In vitro assessment of Clostridium difficile PCR ribotype 002: the most prevalent C. difficile ribotype in the United Kingdom.
(2015-08-25)Background: Clostridium difficile infection (CDI) causes substantial morbidity and healthcare expenditure across Europe. UK prevalence of C. difficile PCR ribotype 027 (NAP1) has declined dramatically recently and other ... -
In vitro cardiovascular system emulator (bioreactor) for the simulation of normal and diseased conditions with and without mechanical circulatory support
(2013-06)This article presents a new device designed to simulate in vitro flow rates, pressures, and other parameters representing normal and diseased conditions of the human cardiovascular system. Such devices are sometimes called ... -
In Vitro Cell Models for Ophthalmic Drug Development Applications
(2016-04-20)Tissue engineering is a rapidly expanding field that aims to establish feasible techniques to fabricate biologically equivalent replacements for diseased and damaged tissues/organs. Emerging from this prospect is the ... -
The in vitro efficacy of haemostatic products in the presence of chemical warfare agents-Sulphur mustard (HD) and VX
(2009-07-28)Haemorrhage remains to be a leading cause of death for trauma victims (Bellamy, 1984). Wound contamination poses an additional complication in the initial management of haemorrhaging wounds, with no specific medical treatment ... -
In vitro efficacy of tavaborole topical solution, 5% after penetration through nail polish on ex vivo human fingernails
(2018-09)Background: Topical antifungal treatments for onychomycosis are applied to clean, unpolished nails for 48 weeks or longer. Patients often wish to mask their infection with nail polish yet there is no evidence to suggest ... -
An in vitro investigation into the effect of glycosaminoglycans on the skin partitioning and deposition of NSAIDs
(2001-08-28)Recently, Solaraze gel (Bioglan, Herts, UK) a topical hyaluronan (HA)/dictofenac formulation for the treatment of actinic keratosis has received regulatory approval in the US, Canada and Europe for the treatment of actinic ... -
An in vitro investigation of the mode of action of hyaluronan as a drug delivery vehicle using circular dichroism
(Royal Society of Medicine Press, 1995) -
In vitro mutation and selection of doubled-haploid Brassica napus lines with improved resistance to Sclerotinia sclerotiorum
(2005-06)This paper describes a new protocol to develop doubled-haploid (DH) Brassica napus lines with improved resistance to Sclerotinia sclerotiorum. In this protocol, haploid seedlings derived from microspore cultures of B. napus ... -
In vitro recognition of a 190 kda putative attachment receptor from the cuticle of Meloidogyne javanica by Pasteuria penetrans spore extract
(1994)Studies were undertaken to develop an improved understanding of the mechanism by which spores of Pasteuria penetrans bind to the cuticle of susceptible nematode hosts. A polyclonal antibody recognized an antigenic ladder ...