Browsing by Author "Guy, Geoffrey"

Now showing items 1-3 of 3

    • Cannabidiol (CBD) is a novel inhibitor for exosome and microvesicle (EMV) release in cancer 

      Kosgodage, Uchini S; Mould, Rhys; Henley, Aine; Nunn, alistair; Guy, Geoffrey; Thomas, E. Louise; Inal, Jameel; Bell, Jimmy; Lange, Sigrun (2018-08-13)
      Exosomes and microvesicles (EMV) are lipid bilayer-enclosed structures, released by cells and involved in intercellular communication through transfer of proteins and genetic material. EMV release is also associated with ...

    • Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells 

      Kosgodage, Uchini S; Uysal-Onganer, Pinar; MacLatchy, Amy; Mould, Rhys; Nunn, Alistair; Guy, Geoffrey; Kraev, Igor; Chatterton, Nicholas; Inal, Jameel; Thomas, E. Louise; Bell, Jimmy; Lange, Sigrun (2019-03-01)
      Glioblastoma multiforme (GBM) is the most common and aggressive form of primary malignant brain tumor in adults, with poor prognosis. Extracellular vesicles (EVs) are key-mediators for cellular communication through transfer ...

    • Cannabidiol Is a Novel Modulator of Bacterial Membrane Vesicles 

      Kosgodage, Uchini S; Matewele, Paul; Awamaria, Brigitte; Kraev, Igor; Warde, Purva; Mastroianni, Giulia; Nunn, alistair; Guy, Geoffrey; Bell, Jimmy; Inal, Jameel; Lange, Sigrun (2019-09-10)
      Membrane vesicles (MVs) released from bacteria participate in cell communication and host-pathogen interactions. Roles for MVs in antibiotic resistance are gaining increased attention and in this study we investigated if ...