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Browsing by Author "Hoebeek, Freek E."
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Cerebellar output controls generalized spike-and-wave discharge occurence
Kros, Lieke; Eelkman Rooda, Oscar; Spanke, Jochen; Alva, Parimala; van Dongen, Marijn; Karapatis, Athanasios; Tolner, Else; Strydis, Christos; Davey, N.; Winkelman, Beerend; Negrello, Mario; Serdijn, Wouter; Steuber, Volker; van den Maagdenberg, Arn; De Zeeuw, Chris I.; Hoebeek, Freek E. (2015-06-01)Disrupting thalamocortical activity patterns has proven to be a promising approach to stop generalized spike-and-wave discharges (GSWDs) characteristic of absence seizures. Here, we investigated to what extent modulation ... -
Combining machine learning and simulations of a morphologically realistic model to study modulation of neuronal activity in cerebellar nuclei
Alva, Parimala; Kroos, Lieke; Eelkman Rooda, Oscar; De Zeeuw, Chris I.; Adams, R.G.; Davey, N.; Hoebeek, Freek E.; Steuber, Volker (2014-07-21)Epileptic absence seizures are characterized by synchronized oscillatory activity in the cerebral cortex that can be recorded as so-called spike-and-wave discharges (SWDs) by electroencephalogram. Although the cerebral ... -
A potential role for the cerebellar nuclei in absence seizures
Alva, Parimala; Kroos, Lieke; Maex, Reinoud; De Zeeuw, Chris I.; Adams, R.G.; Davey, N.; Steuber, Volker; Hoebeek, Freek E. (2013)Poster presented ar CNS 2013