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Browsing by Author "Hyrich, Kimme L."
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Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response
Viatte, Sebastien; Plant, Darren; Han, Buhm; Fu, Bo; Yarwood, Annie; Thomson, Wendy; Symmons, Deborah P.M.; Worthington, Jane; Young, Adam; Hyrich, Kimme L.; Morgan, Ann W.; Wilson, Anthony G.; Isaacs, John D.; Raychaudhuri, Soumya; Barton, Anne (2015-04-28)IMPORTANCE: Advances have been made in identifying genetic susceptibility loci for autoimmune diseases, but evidence is needed regarding their association with prognosis and treatment response. OBJECTIVE: To assess whether ... -
Influence of Social Support, Financial Status, and Lifestyle on the Disparity Between Inflammation and Disability in Rheumatoid Arthritis
Gwinnutt, James M.; Norton, Sam; Hyrich, Kimme L.; Lunt, Mark; Combe, Bernard; Rincheval, Nathalie; Ruyssen‐Witrand, Adeline; Fautrel, Bruno; McWilliams, Daniel F.; Walsh, David A.; Nikiphorou, Elena; Kiely, Patrick D. W.; Young, Adam; Chipping, Jacqueline R.; MacGregor, Alex; Verstappen, Suzanne M. M. (2023-04-24)Objective: To investigate how social support, financial status, and lifestyle influence the development of excess disability in rheumatoid arthritis (RA). Methods: Data were obtained from the Étude et Suivi des Polyarthrites ... -
Not all moderate disease is the same - Identification of disability trajectories among patients with rheumatoid arthritis and moderate disease activity
Pan, Yi; Norton, Sam; Gwinnutt, James M.; Kearsley-Fleet, Lianne; Symmons, Deborah P.M.; Lunt, Mark; Young, Adam; Hyrich, Kimme L.; Verstappen, Suzanne M.M. (2019-05-20)BACKGROUND: United Kingdom guidelines for the use of biologic disease modifying anti-rheumatic drugs (bDMARDS) for rheumatoid arthritis (RA) require patients to have active disease (Disease Activity Score [DAS28] >5.1) and ...