Now showing items 1-4 of 4

    • Hedgehog Signalling in Androgen Independent Prostate Cancer 

      Shaw, Greg; Price, Anna M.; Ktori, Elena; Bisson, Isabelle; Purkis, Patricia E.; McFaul, Siobhan; Oliver, R. Tim D; Prowse, David M. (2008-12-01)
      Objectives: Androgen-deprivation therapy effectively shrinks hormone-naïve prostate cancer, both in the prostate and at sites of distant metastasis. However prolonged androgen deprivation generally results in relapse and ...
    • HPV infection and immunochemical detection of cell-cycle markers in verrucous carcinoma of the penis 

      Stankiewicz, Elzbieta; Kudahetti, Sakunthala C.; Prowse, David M.; Ktori, Elena; Cuzick, Jack; Ambroisine, Laurence; Zhang, Xiaoxi; Watkin, Nicholas; Corbishley, Catherine; Berney, Daniel M. (2009-09-01)
      Penile verrucous carcinoma is a rare disease and little is known of its aetiology or pathogenesis. In this study we examined cell-cycle proteins expression and correlation with human papillomavirus infection in a series ...
    • Human papillomavirus is detected in transitional cell carcinoma arising in renal transplant recipients 

      Husain, Ehab; Prowse, David M.; Ktori, Elena; Shaikh, Taufiq; Yaqoob, Magdi; Junaid, Islam; Baithun, Suhail (2009-11-09)
      Aims: We investigated the role of human papillomavirus HPV in the development of transitional cell carcinoma TCC arising in renal transplant recipients. Methods: Genomic DNA was extracted from 10 m paraffin embedded sections ...
    • The retinoblastoma protein/p16INK4A pathway but not p53 is disrupted by human papillomavirus in penile squamous cell carcinoma 

      Stankiewicz, Elzbieta; Prowse, David M.; Ktori, Elena; Cuzick, Jack; Ambroisine, Laurence; Zhang, Xiaoxi; Kudahetti, Sakunthala; Watkin, Nicholas; Corbishley, Catherine; Berney, Daniel M. (2011-02-01)
      Aims: The pathogenesis of penile squamous cell carcinoma (PSCC) is not well understood. Human papillomavirus (HPV) may be involved in carcinogenesis, but few studies have compared cell-cycle protein expression in HPV ...