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Browsing by Author "Larner, Joanne"
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14C Autoradiography with a novel wafer scale CMOS Active Pixel Sensor
Esposito, M.; Anaxagoras, T.; Larner, Joanne; Allinson, N.M.; Wells, K. (2013-01-07)14C autoradiography is a well established technique for structural and metabolic analysis of cells and tissues. The most common detection medium for this application is film emulsion, which offers unbeatable spatial resolution ... -
Decontamination and Management of Contaminated Hair following a CBRN or HazMat Incident
Matar, Hazem; Tavares Pinhal, Andreia; Amer, Nevine; Barrett, Mark; Thomas, Elliot; Hughes, Philip; Larner, Joanne; Chilcott, Robert (2019-09)This in vitro study evaluated the “triple protocol” of dry decontamination, the ladder pipe system (a method for gross decontamination), and technical decontamination for the decontamination of hair following chemical ... -
Efficacy of Different Hair and Skin Decontamination Strategies with Identification of Associated Hazards to First Responders
Larner, Joanne; Durrant, Adam; Hughes, Philip; Mahalingam, Devanya; Rivers, Samantha; Matar, Hazem; Thomas, Elliot; Barrett, Mark; Tavares Pinhal, Andreia; Amer, Nevine; Hall, Charlotte; Jackson, Toni; Catalani, Valeria; Chilcott, Robert (2019-07-19)Background: Established procedures for mass casualty decontamination involve the deployment of equipment for showering with water (such as the ladder pipe system [LPS] and technical decontamination [TD]). This necessarily ... -
Evaluation of absorbent materials for use as ad hoc dry decontaminants during mass casualty incidents as part of the UK’s Initial Operational Response (IOR)
Chilcott, Robert; Kassouf, Nick; Syed, Sara; Larner, Joanne; Amlôt, Richard (2017-02-02)The UK's Initial Operational Response (IOR) is a revised process for the medical management of mass casualties potentially contaminated with hazardous materials. A critical element of the IOR is the introduction of immediate, ... -
Evaluation of US Federal Guidelines (Primary Response Incident Scene Management [PRISM]) for Mass Decontamination of Casualties During the Initial Operational Response to a Chemical Incident
Chilcott, Robert; Larner, Joanne; Durrant, Adam; Hughes, Philip; Mahalingam, Devanya; Rivers, Samantha; Thomas, Elliot; Amer, Nevine; Barrett, Mark; Matar, Hazem; Pinhal, Andreia; Jackson, Toni; McCarthy-Barnett, Kate; Reppucci, Joseph (2019-06-01)Study objective The aim of this study was to evaluate the clinical and operational effectiveness of US federal government guidance (Primary Response Incident Scene Management [PRISM]) for the initial response phase to ... -
Hybrid in vitro diffusion cell for simultaneous evaluation of hair and skin decontamination: temporal distribution of chemical contaminants
Matar, Hazem; Amer, Nevine; Kansagra, Sneha; Pinhal, Andreia; Thomas, Elliot; Townend, Scott; Larner, Joanne; Chilcott, Robert (2018-11-15)Most casualty or personnel decontamination studies have focused on removing contaminants from the skin. However, scalp hair and underlying skin are the most likely areas of contamination following airborne exposure to ... -
Mass Casualty Decontamination in the United States : An Online Survey of Current Practice
Power, Sarah; Symons, Charles; Carter, Holly; Jones, Emma; Amlôt, Richard; Larner, Joanne; Matar, Hazem; Chilcott, Robert P (2016-08-01)Mass casualty decontamination is a public health intervention that would be employed by emergency responders following a chemical, biological, or radiological incident. The decontamination of large numbers of casualties ... -
Modified static diffusion cells for decontamination modelling
Larner, Joanne; Jones, David R.; Price, Shirley C.; Chilcott, Robert (2010-12-30) -
Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid
Frosini, Sian Marie; Bond, Ross; Loeffler, Annette; Larner, Joanne (2017-11-21)BACKGROUND: Staphylococcal infection of the canine epidermis and hair follicle is amongst the commonest reasons for antimicrobial prescribing in small animal veterinary practice. Topical therapy with fusidic acid (FA) is ... -
Optimisation of a dosing regime for a topical skin protectant (barrier cream)
Chilcott, Robert; Larner, Joanne; Matar, Hazem; Kansagra, Sneha; Theivendran, Baveetharan; Viegas, Vanessa Ann; Goldman, Virginia Streusand (2015)Context: Topical skin protectants (barrier creams) have the potential to reduce or enhance the severity of dermal lesions following exposure to allergens or irritants. Therefore, it is essential that such products are ... -
Optimisation of mass casualty decontamination procedures in vitro
Jones, David R.; Larner, Joanne; Price, Shirley C.; Chilcott, Robert (2010-12-30) -
The United Kingdom’s initial operational response and specialist operational response to CBRN and HazMat incidents: a primer on decontamination protocols for healthcare professionals
Chilcott, Robert; Larner, Joanne; Matar, Hazem (2019-02-01)The UK is currently in the process of implementing a modified response to chemical, biological, radiological and nuclear and hazardous material incidents that combines an initial operational response with a revision of the ... -
Volunteer trials of a novel improvised dry decontamination protocol for use during mass casualty incidents as part of the UK’S Initial Operational Response (IOR)
Amlôt, Richard; Carter, Holly; Riddle, Lorna; Larner, Joanne; Chilcott, Robert P. (2017-06-16)Previous studies have demonstrated that rapid evacuation, disrobing and emergency decontamination can enhance the ability of emergency services and acute hospitals to effectively manage chemically-contaminated casualties. ... -
Whole-body imaging of UV-fluorescent chemical warfare simulants: A potentially quantitative technique for the optimisation of mass casualty decontamination procedures
Larner, Joanne; Matar, Hazem; Jones, David R.; Amlot, Richard; Carter, Holly; Turner, Elizabeth A.; Price, Shirley C.; Chilcott, Robert (2009-07-28)