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Browsing by Author "Modo, Michel"
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Attachment of stem cells to scaffold particles for intra-cerebral transplantation
Bible, Ellen; Chau, David Y.S.; Alexander, Morgan R.; Price, Jack; Shakesheff, Kevin M.; Modo, Michel (2009)Cell-replacement therapy and tissue regeneration using stem cells are of great interest to recover histological damage caused by neuro-degenerative disease or traumatic insults to the brain. To date, the main intra-cerebral ... -
Improving treatment of stroke through nanotechnology
Nicholls, F; Gorenkova, N; Bible, Ellen; Franco, C; Chau, David Y.S.; Tolias, Christos; Shakesheff, Kevin; West, JL; Modo, Michel (CRC Press, 2013) -
Magnetic resonance imaging and tensor-based morphometry in the MPTP non-human primate model of Parkinson's disease
Modo, Michel; Crum, William R; Gerwig, Madeline; Vernon, Anthony C; Patel, Priya; Jackson, Michael J; Rose, Sarah; Jenner, Peter; Iravani, Mahmoud M (2017-07-24)Parkinson's disease (PD) is the second most common neurodegenerative disorder producing a variety of motor and cognitive deficits with the causes remaining largely unknown. The gradual loss of the nigrostriatal pathway is ... -
Neo-vascularization of the stroke cavity by implantation of human neural stem cells on VEGF-releasing PLGA microparticles
Bible, Ellen; Qutachi, Omar; Chau, David Y.S.; Alexander, Morgan R.; Shakesheff, Kevin M.; Modo, Michel (2012-10)Replacing the tissue lost after a stroke potentially provides a new neural substrate to promote recovery. However, significant neurobiological and biotechnological challenges need to be overcome to make this possibility ... -
The support of neural stem cells transplanted into stroke-induced brain cavities by PLGA particles
Bible, Ellen; Chau, David Y.S.; Alexander, Morgan R.; Price, Jack; Shakesheff, Kevin M.; Modo, Michel (2009-06)Stroke causes extensive cellular loss that leads to a disintegration of the afflicted brain tissue. Although transplanted neural stein cells can recover some of the function lost after stroke, recovery is incomplete and ... -
Transplantation of Human NSCs on VEGF-Releasing Microparticle Scaffolds in a Stroke Model
Bible, Ellen; Chau, David Y.S.; Alexander, M. R.; Price, J.; Shakesheff, Kevin M.; Modo, Michel (2010)