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Browsing by Author "Robbins, Trevor W"
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Action sequence learning, habits, and automaticity in obsessive-compulsive disorder
Banca, Paula; Herrojo Ruiz, Maria; Gonzalez-Zalba, Miguel Fernando; Biria, Marjan; Marzuki, Aleya A; Piercy, Thomas; Sule, Akeem; Fineberg, Naomi A; Robbins, Trevor W (2024-05-09)This study investigates the goal/habit imbalance theory of compulsion in obsessive-compulsive disorder (OCD), which postulates enhanced habit formation, increased automaticity, and impaired goal/habit arbitration. It ... -
Action-Outcome Knowledge Dissociates From Behavior in Obsessive-Compulsive Disorder Following Contingency Degradation
Vaghi, Matilde M; Cardinal, Rudolf N; Apergis-Schoute, Annemieke M; Fineberg, Naomi A; Sule, Akeem; Robbins, Trevor W (2019-02-01)BACKGROUND: In obsessive-compulsive disorder (OCD), actions persist despite being inappropriate to the situation and without relationship to the overall goal. Dysfunctional beliefs have traditionally been postulated to ... -
Computational modelling reveals contrasting effects on reinforcement learning and cognitive flexibility in stimulant use disorder and obsessive-compulsive disorder : remediating effects of dopaminergic D2/3 receptor agents
Kanen, Jonathan W; Ersche, Karen D; Fineberg, Naomi; Robbins, Trevor W; Cardinal, Rudolf N (2019-08-01)RATIONALE: Disorders of compulsivity such as stimulant use disorder (SUD) and obsessive-compulsive disorder (OCD) are characterised by deficits in behavioural flexibility, some of which have been captured using probabilistic ... -
A Randomized Trial Directly Comparing Ventral Capsule and Anteromedial Subthalamic Nucleus Stimulation in Obsessive-Compulsive Disorder: Clinical and Imaging Evidence for Dissociable Effects
Tyagi, Himanshu; Apergis-Schoute, Annemieke M; Akram, Harith; Foltynie, Tom; Limousin, Patricia; Drummond, Lynne; Fineberg, Naomi; Matthews, Keith; Jahanshahi, Marjan; Robbins, Trevor W; Sahakian, Barbara J; Zrinco, Ludvic; Hariz, Marwan; Joyce, Eileen M (2019-05-01)Background Deep brain stimulation (DBS) is an emerging treatment for severe obsessive-compulsive disorder (OCD). We compared the efficacy of ventral capsule/ventral striatal (VC/VS) and anteromedial subthalamic nucleus ...