Browsing by Author "Smith, S.J."

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    • The effects of SB 206284A, a novel neuronal Ca channel antagonist in models of cerebral ischaemia 

      Wood, N.; Barone, F.C.; Benham, C.D.; Brown, T.H.; Campbell, C.A.; Cooper, D.C.; Evans, M.L.; Feuerstein, G.; Hamilton, T.C.; Harries, M.; King, P.D.; Meakin, J.E.; Murkitt, J.L.; Patel, S.; Price, W.J.; Roberts, J.C.; Rothaul, A.L.; Samson, N.A.; Smith, S.J.; Hunter, A.J. (1997)
      The effects of SB 206284A, 1-[7-(4-benzyloxyphenoxy)heptyl] piperidine hydrochloride, have been investigated in vitro on calcium and sodium currents in rat-cultured dorsal root ganglion (DRG) neurones and potassium-mediated ...

    • SB 201823-A, A neuronal Ca antagonist is neuroprotective in two models of cerebral ischaemia 

      Benham, C.D.; Brown, T.H.; Cooper, D.C.; Evans, M.L.; Harries, M.; Herdon, H.J.; Meakin, J.E.; Murkitt, K.L.; Patel, S.; Roberts, J.C.; Rothaul, A.L.; Smith, S.J.; Wood, N.; Hunter, A.J. (1993)
      We have characterised the Ca2+ channel blocking properties of a new non-peptide Ca2+ channel antagonist, SB 201823-A, in cultures of rat sensory neurones. The IC50 for SB 201823-A against total Ca2+ current in sensory ...