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Changes in the zymogenic cell populations of the abomasa of sheep infected with Haemonchus contortus
Scott, I.; Stear, M.J.; Irvine, J.; Dick, A.; Wallace, D.S.; McKellar, Quintin (1998-06)The effects of dietary urea supplementation and of a 10-week trickle infection regime, simulating chronic exposure to Haemonchus contortus, on the zymogenic population of the abomasa of Hampshire Down lambs was examined, ... -
Comparison of four methods for the determination of plasma pepsinogen concentration
Scott, I.; Stear, M.J.; McKellar, Quintin (1995-11)Four methods for estimating plasma pepsinogen concentrations were compared to determine the most suitable for routine use. Three of the methods were colorimetric assays which used glycine-buffered albumin, albumin, or ... -
The distribution of pepsinogen within the abomasa of cattle and sheep infected with Ostertagia spp. and sheep infected with Haemonchus contortus
Scott, I.; Dick, A.; Irvine, J.; Stear, M.J.; McKellar, Quintin (1999-03-31)The effect of nematode infections on the production of pepsinogen by ruminants was investigated immunohistochemically and biochemically. Abomasal tissues were collected from parasite-naive cattle and sheep, from sheep ... -
Eosinophilia as a marker of resistance to Teladorsagia circumcincta in Scottish Blackface lambs
Stear, M.J.; Henderson, N.G.; Kerr, A.; McKellar, Quintin; Mitchell, S.; Seeley, C.; Bishop, S.C. (2002-05) -
Fructosamine concentration and resistance to natural, predominantly Teladorsagia circumcincta infection
Stear, M.J.; Eckersall, P.D.; Graham, P.A.; McKellar, Quintin; Mitchell, S.; Bishop, S.C. (2001-08)Fructosamine con cent rations reflect protein status and because infection with Teladorsagia circumcineta can induce a relative protein deficiency, we examined the usefulness of fructosamine concentrations as markers of ... -
The genetic basis of resistance to Ostertagia circumcincta in lambs
Stear, M.J.; Bairden, K.; Bishop, S.C.; Buitkamp, J.; Duncan, J.L.; Gettinby, G.; McKellar, Quintin; Park, M.; Parkins, J.J.; Reid, S.W.J. (1997-09)The relationship between Ostertagia (Teladorsagia) circumcincta and sheep is one of the best understood host-parasite relationships in any species. The key components of resistance have been quantified, the extent of genetic ... -
The genetic control of IgA activity against Teladorsagia circumcincta and its association with parasite resistance in naturally infected sheep
Strain, S.A.J.; Bishop, S.C.; Henderson, N.G.; Kerr, A.; McKellar, Quintin; Mitchell, S.; Stear, M.J. (2002-05)Previous studies in deliberately infected sheep have shown an association between IgA activity against 4th-stage larvae of Teladorsagia circumcincta and parasite growth, development and fecundity. The purpose of this ... -
Genetic parameters for faecal egg count following mixed, natural, predominantly Ostertagia circumcinta infection and relationships with live weight in young lambs
Bishop, S.C.; Bairden, K.; McKellar, Quintin; Park, M.; Stear, M.J. (1996-12)Faecal egg counts and live weights were measured on approximately 200 predominantly twin-born Scottish Blackface lambs each year for 3 years, from 2 to 6 months of age. Measurements were made at 4-week intervals following ... -
How hosts control worms
Stear, M.J.; Bairden, K.; Duncan, J.L.; Holmes, P.H.; McKellar, Quintin; Park, M.; Strain, S.; Murray, M.; Bishop, S.C.; Gettinby, G. (1997-09-04)Nematodes are a major cause of disease and death in humans, domestic animals and wildlife. Understanding why some individuals suffer severely whereas others exposed to the same infection remain healthy may assist in the ... -
The influence of age on the variation among sheep in susceptibility to natural nematode infection
Stear, M.J.; Mitchell, S.; Strain, S.; Bishop, S.C.; McKellar, Quintin (2000-03-28)A longitudinal study of faecal nematode egg counts was made in naturally infected Scottish Blackface sheep over two grazing seasons to 75 weeks of age. Although egg counts were lower in the second grazing season the variation ... -
The influence of relative resistance and urea-supplementation on deliberate infection with<i> Teladorsagia circumcincta during winter
Stear, M.J.; Bairden, K.; Duncan, J.L.; Eckersall, P.D.; Fishwick, G.; Graham, P.A.; Holmes, P.H.; McKellar, Quintin; Mitchell, S.; Murray, M. (2000-12-20)The consequences for lambs of infection over the winter with Teladorsagia circumcincta were quantified by deliberate, trickle infection of selected animals at 7 months of age. Infected and control uninfected animals were ... -
Influence of supplementation with dietary soyabean meal on resistance to haemonchosis in Hampshire Down lambs
Wallace, D.S.; Bairden, K.; Duncan, J.L.; Fishwick, G.; Gill, M.; Holmes, P.H.; McKellar, Quintin; Murray, M.; Parkins, J.J.; Stear, M.J. (1995-05)The influence of dietary protein supplementation on resistance to haemonchosis was examined in Hampshire down lambs fed either a basal diet or a diet supplemented with soyabean. At seven months of age the lambs were ... -
An ovine lymphocyte antigen is associated with reduced faecal egg counts in four-month-old lambs following natural, predominantly Ostertagia circumcincta infection
Stear, M.J.; Bairden, K.; Bishop, S.C.; Buitkamp, J.; Epplen, J.T.; Gostomski, D.; McKellar, Quintin; Schwaiger, F.W.; Wallace, D.S. (1996-04)Ten lymphocyte antigens were defined in a flock of Scottish Blackface sheep known to be naturally exposed to infection with Ostertagia circumcincta. Population and family studies suggested that the 10 antigens were products ... -
An ovine Major histocompatibility complex DRB1 allele is associated with low faecal egg counts following natural, predominantly Ostertagia circumcincta infection
Schwaiger, F.W.; Gostomski, D.; Stear, M.J.; Duncan, J.L.; McKellar, Quintin; Epplen, J.T.; Buitkamp, J. (1995-07)Infection with Ostertagia circumcincta is a major constraint on sheep production in temperate areas of the world. A potential control strategy is the use of genetically resistant sheep. Therefore we examined the association ... -
The processes influencing the distribution of parasitic nematodes among naturally infected lambs
Stear, M.J.; Bairden, K.; Bishop, S. C.; Gettinby, G.; McKellar, Quintin; Park, M.; Strain, S.; WALLACE, D.S. (1998-08)The impact of mixed, nematode infection upon a group of animals will depend upon the number of nematodes present, how they are distributed among hosts and whether individuals that are heavily parasitized with one species ... -
The relationship between the number and size of nematodes in the abomasum and the concentration of pepsinogen in ovine plasma
Stear, M.J.; Bairden, K.; McKellar, Quintin; Scott, I.; Strain, S.; Bishop, S.C. (1999-08)Six-month-old lambs that had been naturally infected with predominantlyTeladorsagia (Ostertagia) circumcinctawere tested for plasma pepsinogen concentrations because pepsinogen concentrations may reflect the extent of ... -
The repeatability of faecal egg counts, peripheral eosinophil counts, and plasma pepsinogen concentrations during deliberate infections with Ostertagia circumcincta
Stear, M.J.; Bishop, S.C.; Duncan, J.L.; McKellar, Quintin; Murray, M. (1995-03)Faecal egg counts, peripheral blood eosinophil counts and plasma pepsinogen concentrations were monitored during 2 successive, deliberate infections in 24 Scottish Blackface sheep. For all 3 techniques, the repeatability ...