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Browsing by Author "Sutcliffe, M. J."
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Comparative modelling of cytochromes P450
Kirton, S. B.; Baxter, C. A.; Sutcliffe, M. J. (2002-03-31)The superfamily of enzymes known as the cytochromes P450 (P450s) comprises a wide-ranging class of proteins with diverse functions. They are known, amongst other things, to be involved in the hormonal regulation of metabolism ... -
In silico methods for predicting ligand binding determinants of cytochromes P450
de Groot, M. J.; Kirton, S. B.; Sutcliffe, M. J. (2004)A large number of computational methodologies have been used to predict, and thus help explain, the metabolism catalysed by the enzymes of the cytochrome P450 superfamily (P450s). A summary of the methodologies and resulting ...