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    • Glucose stimulates somatostatin secretion in pancreatic δ-cells by cAMP-dependent intracellular Ca2+ release 

      Denwood, Geoffrey; Tarasov, Andrei; Salehi, Albert; Vergari, Elisa; Ramracheya, Reshma; Takahashi, Harumi; Nikolaev, Viacheslav O; Seino, Susumo; Gribble, Fiona; Reimann, Frank; Rorsman, Patrik; Zhang, Quan (2019-09-02)
      Somatostatin secretion from pancreatic islet δ-cells is stimulated by elevated glucose levels, but the underlying mechanisms have only partially been elucidated. Here we show that glucose-induced somatostatin secretion ...