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Browsing by Author "Tel, Banu C."
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Continuous subcutaneous infusion of pramipexole protects against lipopolysaccharide-induced dopaminergic cell death without affecting the inflammatory response
Iravani, Mahmoud M.; Sadeghian, Mona; Leung, Clement C. M.; Tel, Banu C.; Rose, Sarah; Schapira, Anthony H.; Jenner, Peter (2008-08)The D2/D3 dopamine receptor agonist pramipexole, protects against toxin-induced dopaminergic neuronal destruction but its mechanism of action is unknown. Inflammation following glial cell activation contributes to cell ... -
GDNF reverses priming for dyskinesia in MPTP-treated, L-DOPA-primed common marmosets
Iravani, Mahmoud M.; Costa, S.; Jackson, M. J.; Tel, Banu C.; Cannizzaro, C.; Pearce, R. K. B.; Jenner, P. (2001-02)Parkinson's disease (PD) is associated with a progressive loss of dopamine neurons in the substantia nigra and degeneration of dopaminergic terminals in the striatum. Although L-DOPA treatment provides the most effective ...