Browsing by Author "Van Niel, M.B."

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    • A New Pyridazine Series of GABAA α5 Ligands 

      Van Niel, M.B.; Wilson, K.; Adkins, C.H.; Atack, J.R.; Castro, J.L.; Clarke, D.E.; Fletcher, S.; Gerhard, U.; Mackey, M.M.; Malpas, S.; Maubach, K.; Newman, R.; O'Connor, D.; Pillai, G.V.; Simpson, P.B.; Thomas, S.R.; MacLeod, A.M. (2005-09-22)
      Screening of the Merck compound collection identified 6 as an unusually simple, low molecular weight hit with moderate affinity for GABAA receptors. The structural novelty of 6, compared to our advanced series of GABAA α5 ...