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Browsing by Author "Viatte, Sebastien"
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Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response
Viatte, Sebastien; Plant, Darren; Han, Buhm; Fu, Bo; Yarwood, Annie; Thomson, Wendy; Symmons, Deborah P.M.; Worthington, Jane; Young, Adam; Hyrich, Kimme L.; Morgan, Ann W.; Wilson, Anthony G.; Isaacs, John D.; Raychaudhuri, Soumya; Barton, Anne (2015-04-28)IMPORTANCE: Advances have been made in identifying genetic susceptibility loci for autoimmune diseases, but evidence is needed regarding their association with prognosis and treatment response. OBJECTIVE: To assess whether ... -
HLA-DRB1 Amino Acid Positions 11/13, 71, and 74 Are Associated With Inflammation Level, Disease Activity, and the Health Assessment Questionnaire Score in Patients With Inflammatory Polyarthritis
Ling, Stephanie F; Viatte, Sebastien; Lunt, Mark; Van Sijl, Alper M; Silva-Fernandez, Lucia; Symmons, Deborah P M; Young, Adam; Macgregor, Alexander J; Barton, Anne (2016-06-06)OBJECTIVE: Rheumatoid arthritis (RA) susceptibility HLA-DRB1 haplotypes based on amino acid positions 11/13, 71, and 74 predict radiographic damage. The mechanism of action is unknown, but it may be mediated by inflammation. ...