Browsing by Author "Viljoen, Adie"

Now showing items 1-5 of 5

    • A comparative study of blood endotoxin detection in haemodialysis patients 

      Wong, Jonathan; Davies, Nathan; Jeraj, Hasan; Vilar, Enric; Viljoen, Adie; Farrington, Kenneth (2016-07-30)
      BACKGROUND: Endotoxemia is commonly reported in patients receiving haemodialysis and implicated in the pathogenesis of systemic inflammation. The Limulus Amoebocyte Lysate (LAL) assay is the most commonly used blood endotoxin ...

    • Endotoxin detection in end-stage kidney disease 

      Wong, Jonathan; Jeraj, Hassan; Vilar, Enric; Viljoen, Adie; Farrington, Kenneth (2015-01-01)
      Aims: Endotoxin detection assays are not validated for use in end-stage kidney disease (ESKD). We investigated the accuracy and precision of the kinetic turbidimetric Limulus amoebocyte lysate (LAL) assay to detect endotoxin ...

    • Plasma Levels of Middle Molecules to Estimate Residual Kidney Function in Haemodialysis without Urine Collection 

      Vilar, Enric; Boltiador, Capella; Wong, Jonathan; Viljoen, Adie; Machado, Ashwini; Uthayakumar, Arani; Farrington, Kenneth (2015-12-02)
      BACKGROUND: Residual Kidney Function (RKF) is associated with survival benefits in haemodialysis (HD) but is difficult to measure without urine collection. Middle molecules such as Cystatin C and β2-microglobulin accumulate ...

    • Predicting residual kidney function in hemodialysis patients using serum β-trace protein and β2-microglobulin 

      Wong, Jonathan; Sridharan, Sivakumar; Berdeprado, Jocelyn; Viljoen, Adie; Vilar Hall, Enric; Wellsted, David; Farrington, Kenneth (2016-02-16)
      Residual kidney function (RKF) contributes significant solute clearance in hemodialysis patients. Kidney Diseases Outcomes Quality Initiative (KDOQI) guidelines suggest that hemodialysis dose can be safely reduced in those ...

    • Removal and rebound kinetics of cystatin C in high-flux hemodialysis and hemodiafiltration 

      Vilar, Enric; Boltiador, Capella; Viljoen, Adie; Machado, Ashwini; Farrington, Kenneth (2014-07-07)
      BACKGROUND AND OBJECTIVES: Cystatin C is a 13.3 kD middle molecule of similar size to β2-microglobulin and a marker of GFR in CKD. This study aimed to determine cystatin C kinetics in hemodialysis to understand whether ...