Browsing by Author "Whiteman, Matthew"

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    • Glial metabolism of quercetin reduces its neurotoxic potential 

      Vafeiadou, Katerina; Vauzour, David; Rodriguez-Mateos, Ana; Whiteman, Matthew; Williams, Robert J.; Spencer, Jeremy P. E. (2008-10-15)
      The neuroprotective effects of flavonoids will ultimately depend on their interaction with both neuronal and glial cells. In this study, we show that the potential neurotoxic effects of quercetin are modified by glial cell ...

    • The reaction of flavonoid metabolites with peroxynitrite 

      Pollard, Susan E.; Kuhnle, Gunter G. C.; Vauzour, David; Vafeiadou, Katerina; Tzounis, Xenofon; Whiteman, Matthew; Rice-Evans, Catherine; Spencer, Jeremy P. E. (2006-12-01)
      There is much interest in the bioactivity of in vivo flavonoid metabolites. We report for the first time the hierarchy of reactivity of flavonoid metabolites with peroxynitrite and characterise novel reaction products. ...