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Browsing by Author "Whitmore, A. C."
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Ig isotype switching in B lymphocytes : A method for estimating isotype switch frequency in cloned B cell lymphomas
Whitmore, A. C.; Prowse, David M.; Arnold, L. W.; Haughton, G. (1989)We have developed a method for enumerating the frequency of Ig isotype switching in clones of B cells. The method adapts Poisson statistics to analyze the distribution of amounts of switched isotype produced by multiple ... -
Ig isotype switching in B lymphocytes : The effect of T cell-derived interleukins, cytokines, cholera toxin, and antigen on isotype switch frequency of a cloned B cell lymphoma
Whitmore, A. C.; Prowse, David M.; Haughton, G.; Arnold, L. W. (1991)The murine B cell lymphoma CH12.LX, which bears cell surface IgM specific for the phosphatidyl choline epitope of sheep red blood cells, is capable of spontaneous isotype switching in vitro. Switching to IgG3, IgG1, IgG2b, ...