Browsing by Author "Whitwell, Harry J."

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    • The Human Body as a Super Network : Digital Methods to Analyze the Propagation of Aging 

      Whitwell, Harry J.; Bacalini, Maria Giulia; Blyuss, Oleg; Chen, Shangbin; Garagnani, Paolo; Gordleeva, Susan Yu; Jalan, Sarika; Ivanchenko, Mikhail; Kanakov, Oleg; Kustikova, Valentina; Mariño, Ines P.; Meyerov, Iosif; Ullner, Ekkehard; Franceschi, Claudio; Zaikin, Alexey (2020-05-25)
      Biological aging is a complex process involving multiple biological processes. These can be understood theoretically though considering them as individual networks—e.g., epigenetic networks, cell-cell networks (such as ...

    • Improved early detection of ovarian cancer using longitudinal multimarker models 

      Whitwell, Harry J.; Worthington, Jenny; Blyuss, Oleg; Gentry-Maharaj, Aleksandra; Ryan, Andy; Gunu, Richard; Kalsi, Jatinderpal; Menon, Usha; Jacobs, Ian; Zaikin, Alexey; Timms, John F. (2020-03-17)
      Background: Ovarian cancer has a poor survival rate due to late diagnosis and improved methods are needed for its early detection. Our primary objective was to identify and incorporate additional biomarkers into longitudinal ...

    • Parenclitic and Synolytic Networks Revisited 

      Nazarenko, Tatiana; Whitwell, Harry J.; Blyuss, Oleg; Zaikin, Alexey (2021-10-20)
      Parenclitic networks provide a powerful and relatively new way to coerce multidimensional data into a graph form, enabling the application of graph theory to evaluate features. Different algorithms have been published for ...