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Browsing by Author "Zhang, T."
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Action potential changes associated with the inhibitory effects on voltage-gated sodium current of hippocampal CA1 neurons by silver nanoparticles
Liu, Z.; Ren, Guogang; Zhang, T.; Zhang, Z. (2009)Nano-sized materials are now being used in medicine, biotechnology, energy, and environmental technology. Although a wide and growing number of applications for nanomaterials exist, there are limited studies available on ... -
Effects of nano CuO on hippocampal neurons and differentiated PC12 cells
Xu, L.; Zhao, J.; Liu, S.; Zhang, T.; Ren, Guogang; Yang, Z. (2008)The effects of nanoparticles of CuO on delayed rectifier potassium current (Ik) were studied in acutely isolated CA1 pyramidal neurons of rat hippocampus by using the whole-cell patch-clamp techniques and the effects on ... -
In vitro study on influence of nano particles of CuO on CA1 pyramidal neurons of rat hippocampus potassium currents
Xu, L.; Zhao, J.; Zhang, T.; Yang, Z.; Ren, Guogang (2008)The effects of nano particles of CuO on voltage-dependent potassium currents were studied in acutely isolated CA1 pyramidal neurons of rat hippocampus using the whole-cell patch-clamp techniques. Nano particles of CuO had ... -
Influences of nanoparticle zinc oxide on acutely isolated rat hippocampal CA3 pyramidal neurons
Zhao, J.; Xu, L.; Zhang, T.; Ren, Guogang; Yang, Z. (2009)The effects of zinc oxide nanoparticles (nano-ZnO) on the properties of voltage-dependent sodium, potassium currents and evoked action potentials were studied in acutely isolated rat hippocampal CA3 pyramidal neurons at ... -
Nano-CuO inhibited voltage-gated sodium current of hippocampal CA1 neurons via reactive oxygen species but independent from G-proteins pathway
Liu, Z.; Liu, S.; Ren, Guogang; Zhang, T.; Yang, Z. (2011)The aim of this study was to investigate the effects of nano-CuO on voltage-gated sodium current (INa) in hippocampal CA1 neurons. The results suggested that nano-CuO inhibited amplitudes of INa currents and prolonged peak ... -
Nano-zinc oxide damages spatial cognition capability via over-enhanced long-term potentiation in hippocampus of Wistar rats
Han, D.D.; Tian, Y.T.; Zhang, T.; Ren, Guogang; Yang, Z. (2011)This study focused on the effects of zinc oxide nanoparticles (nano-ZnO) on spatial learning and memory and synaptic plasticity in the hippocampus of young rats, and tried to interpret the underlying mechanism. Rats were ...