dc.contributor.author | Hoffman, Richard | |
dc.contributor.author | Madden, Angela | |
dc.contributor.author | Ranjbar, Golnaz | |
dc.date.accessioned | 2017-09-14T16:40:02Z | |
dc.date.available | 2017-09-14T16:40:02Z | |
dc.date.issued | 2016-03-30 | |
dc.identifier.citation | Hoffman , R , Madden , A & Ranjbar , G 2016 , ' Inhibition of the glycaemic response by onion : a comparison between lactose-tolerant and lactose-intolerant adults ' , European Journal of Clinical Nutrition , vol. 70 , pp. 1089-1091 . https://doi.org/10.1038/ejcn.2016.44 | |
dc.identifier.issn | 1476-5640 | |
dc.identifier.uri | http://hdl.handle.net/2299/19386 | |
dc.description | This document is the Accepted Manuscript of the following article: R Hoffman, G Ranjbar and A M Madden, ‘Inhibition of the glycaemic response by onion: a comparison between lactose-tolerant and lactose-intolerant adults’, European Journal of Clinical Nutritin, (2016), 70: 1089-1091. The Version of Record is available online at doi: 10.1038/ejcn.2016.44. | |
dc.description.abstract | This pilot study compared inhibition of the glycaemic response to glucose by a dietary source of quercetin glucosides (onion) in lactose-tolerant adults (n = 12) and lactose-intolerant adults (n = 12). We hypothesised that lactose-intolerant people (who do not express lactase) will retain intact quercetin glucosides that can inhibit glucose uptake via the glucose transporter SGLT1 whereas lactose-tolerant people (who do express lactase) will hydrolyse quercetin glucosides to free quercetin which does not inhibit glucose uptake. In a glucose tolerance test, reduction of peak glucose levels by an onion meal was higher in lactose-intolerant people than lactose-tolerant people (44.2% versus 19.3%, p = 0.04). Incremental area under the blood glucose curve was reduced more in lactose-intolerant people, but was not statistically significantly (54.5% versus 42.1%, p = 0.42). A diet containing quercetin glucosides may be of greater benefit for glycaemic control in lactose-intolerant people than in lactose-tolerant people. | en |
dc.format.extent | 3 | |
dc.format.extent | 577997 | |
dc.language.iso | eng | |
dc.relation.ispartof | European Journal of Clinical Nutrition | |
dc.subject | Glycaemic index | |
dc.subject | Mediterranean diet | |
dc.subject | lactase | |
dc.subject | onion | |
dc.subject | quercetin | |
dc.title | Inhibition of the glycaemic response by onion : a comparison between lactose-tolerant and lactose-intolerant adults | en |
dc.contributor.institution | Agriculture, Food and Veterinary Sciences | |
dc.contributor.institution | Geography, Environment and Agriculture | |
dc.contributor.institution | Microbiology and Biotechnology | |
dc.contributor.institution | Food Policy, Nutrition and Diet | |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Department of Biological and Environmental Sciences | |
dc.contributor.institution | Allied Health Professions | |
dc.contributor.institution | Weight and Obesity Research Group | |
dc.contributor.institution | Biosciences Research Group | |
dc.description.status | Peer reviewed | |
dc.date.embargoedUntil | 2016-09-30 | |
rioxxterms.versionofrecord | 10.1038/ejcn.2016.44 | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |