Studies of Unexplained Inflammation in Haemodialysis and the Role of Endotoxin
The work in this thesis would not have been possible without the support and guidance from my supervisors Professor Ken Farrington and Dr Enric Vilar. It has been my privilege to have worked under their mentorship and they have taught me a tremendous amount of nephrology, research and have inspired me to strive to continue to become a better clinician to patients. I would like to express my sincere thanks and gratitude to them for their encouragement and providing me with this opportunity for research. I would like to thank my research colleagues at the Lister renal research unit including Jocelyn Berdeprado, Santee Navjee, Lily Wilkinson, Dr Sivakumar Sridharan, Dr Sivaramakrishnan Ramanarayanan, Dr Raja Mohammed Kaja Kamal for their support and companionship. I am grateful to Mr Jim Jeraj, Dr Adie Viljoen, Dr Ashish Patidar and Dr David Wellsted for their advice on methodological and statistical issues. I would like to express my gratitude to my collaborators including Professor Toru Obata, Dr Nathan Davies, Dr Kaatje Lenaerts and Dr Malcolm Finkelman for their expertise and support in my research studies. I would like to express thanks to all the patients and volunteers who participated in the studies. Without their kind participation in this study, none of this work would have been possible. I would like to acknowledge the Sasakawa Foundation and the Renal Association for their generosity and providing me with travel bursaries which enabled me to develop collaborative relationships with international research groups in Japan and the Netherlands. I would also like to thank Associates of Cape Cod Inc. for supporting the costs of carrying out (1-3)-β-D glucan assays. Finally, I would like to thank my wife Lisa for her invaluable support and encouragement during challenging times and my parents for their unconditional love and support in all aspects of my life.
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