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dc.contributor.authorBarss, Trevor
dc.contributor.authorCollins, Dave
dc.contributor.authorMiller, Dylan
dc.contributor.authorPujari, Amit
dc.date.accessioned2021-08-23T14:45:01Z
dc.date.available2021-08-23T14:45:01Z
dc.date.issued2021-05-17
dc.identifier.citationBarss , T , Collins , D , Miller , D & Pujari , A 2021 , ' Indirect Vibration of the Upper Limbs Alters Transmission Along Spinal but Not Corticospinal Pathways ' , Frontiers in Human Neuroscience , vol. 15 , 617669 . https://doi.org/10.3389/fnhum.2021.617669
dc.identifier.issn1662-5161
dc.identifier.otherPURE: 13381732
dc.identifier.otherPURE UUID: e239b0d1-02d5-46b0-97ee-6bc090b50be9
dc.identifier.otherJisc: b3cdb7a259aa47a2937f3257231597f1
dc.identifier.otherJisc: b3cdb7a259aa47a2937f3257231597f1
dc.identifier.otherScopus: 85107046853
dc.identifier.otherORCID: /0000-0003-1688-4448/work/99079148
dc.identifier.urihttp://hdl.handle.net/2299/25000
dc.descriptionFunding Information: Support for this research was provided by the Churchill Travelling Fellowship through Winston Churchill Memorial Trust (to AP) and a Campus Alberta Neuroscience Postdoctoral Fellowship (TB). The vibration stimulation device used in this work was supported by funding from the Scottish Funding Council, United Kingdom (SFC) (to AP). Publisher Copyright: © Copyright © 2021 Barss, Collins, Miller and Pujari.
dc.description.abstractThe use of upper limb vibration (ULV) during exercise and rehabilitation continues to gain popularity as a modality to improve function and performance. Currently, a lack of knowledge of the pathways being altered during ULV limits its effective implementation. Therefore, the aim of this study was to investigate whether indirect ULV modulates transmission along spinal and corticospinal pathways that control the human forearm. All measures were assessed under CONTROL (no vibration) and ULV (30 Hz; 0.4 mm displacement) conditions while participants maintained a small contraction of the right flexor carpi radialis (FCR) muscle. To assess spinal pathways, Hoffmann reflexes (H-reflexes) elicited by stimulation of the median nerve were recorded from FCR with motor response (M-wave) amplitudes matched between conditions. An H-reflex conditioning paradigm was also used to assess changes in presynaptic inhibition by stimulating the superficial radial (SR) nerve (5 pulses at 300Hz) 37 ms prior to median nerve stimulation. Cutaneous reflexes in FCR elicited by stimulation of the SR nerve at the wrist were also recorded. To assess corticospinal pathways, motor evoked potentials (MEPs) elicited by transcranial magnetic stimulation of the contralateral motor cortex were recorded from the right FCR and biceps brachii (BB). ULV significantly reduced H-reflex amplitude by 15.7% for both conditioned and unconditioned reflexes (24.0 ± 15.7 vs. 18.4 ± 11.2% Mmax; p < 0.05). Middle latency cutaneous reflexes were also significantly reduced by 20.0% from CONTROL (−1.50 ± 2.1% Mmax) to ULV (−1.73 ± 2.2% Mmax; p < 0.05). There was no significant effect of ULV on MEP amplitude (p > 0.05). Therefore, ULV inhibits cutaneous and H-reflex transmission without influencing corticospinal excitability of the forearm flexors suggesting increased presynaptic inhibition of afferent transmission as a likely mechanism. A general increase in inhibition of spinal pathways with ULV may have important implications for improving rehabilitation for individuals with spasticity (SCI, stroke, MS, etc.).en
dc.language.isoeng
dc.relation.ispartofFrontiers in Human Neuroscience
dc.rightsOpen
dc.subjectH-reflex
dc.subjectcutaneous reflex
dc.subjectelectromyography
dc.subjectindirect vibration
dc.subjectmotor evoked potential
dc.subjectsensorimotor integration
dc.subjecttranscranial magnetic stimulation
dc.subjectupper limb vibration
dc.subjectNeuropsychology and Physiological Psychology
dc.subjectNeurology
dc.subjectPsychiatry and Mental health
dc.subjectBiological Psychiatry
dc.subjectBehavioral Neuroscience
dc.titleIndirect Vibration of the Upper Limbs Alters Transmission Along Spinal but Not Corticospinal Pathwaysen
dc.contributor.institutionDepartment of Engineering and Technology
dc.contributor.institutionSchool of Physics, Engineering & Computer Science
dc.contributor.institutionBioEngineering
dc.contributor.institutionCentre for Engineering Research
dc.description.statusPeer reviewed
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85107046853&partnerID=8YFLogxK
dc.relation.schoolSchool of Physics, Engineering & Computer Science
dc.description.versiontypeFinal Published version
dcterms.dateAccepted2021-05-17
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.3389/fnhum.2021.617669
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue
herts.rights.accesstypeOpen


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