Browsing University of Hertfordshire by Author "Duchen, Michael R"

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    • Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells 

      Haythorne, Elizabeth; Rohm, Maria; van de Bunt, Martijn; Brereton, Melissa F; Tarasov, Andrei I; Blacker, Thomas S; Sachse, Gregor; Silva Dos Santos, Mariana; Terron Exposito, Raul; Davis, Simon; Baba, Otto; Fischer, Roman; Duchen, Michael R; Rorsman, Patrik; MacRae, James I; Ashcroft, Frances M (2019-06-06)
      Diabetes is a global health problem caused primarily by the inability of pancreatic β-cells to secrete adequate levels of insulin. The molecular mechanisms underlying the progressive failure of β-cells to respond to glucose ...