Browsing University of Hertfordshire by Author "Essex, Samantha"

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    • Investigation of the protein alkylation sites of the STAT3:STAT3 inhibitor Stattic by mass spectrometry 

      Heidelberger, Sibylle; Zinzalla, Giovanna; Antonow, Dyeison; Essex, Samantha; Piku Basu, B.; Palmer, Jonathan; Husby, Jarmila; Jackson, Paul J. M.; Rahman, Khondaker M.; Wilderspin, Andrew F.; Zloh, Mire; Thurston, David E. (2013-08-15)
      STAT3 (Signal Transducer and Activator of Transcription factor 3) is constitutively active in a wide range of human tumours. Stattic is one of the first non-peptidic small molecules reported to inhibit formation of the ...