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Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse
Lu, Qi Long; Mann, Christopher J; Lou, Fang; Bou-Gharios, George; Morris, Glenn E; Xue, Shao-an; Fletcher, Sue; Partridge, Terence A; Wilton, Stephen D (2003)As a target for gene therapy, Duchenne muscular dystrophy (DMD) presents many obstacles but also an unparalleled prospect for correction by alternative splicing. The majority of mutations in the dystrophin gene occur in ...