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Browsing University of Hertfordshire by Author "Strain-Damerell, C."
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Evaluation of recombinant cytochrome p450 enzymes as an in vitro system for metabolic clearance predictions
Stringer, R.A.; Strain-Damerell, C.; Nicklin, P.; Houston, J.B. (2009-05-01)The aim of this study was to explore the potential of recombinant cytochrome P450 (P450) enzymes for human metabolic clearance prediction. The relative abundance and relative activity approaches were compared as methods ...