Browsing University of Hertfordshire by Author "Trefny, Marcel P"

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    • Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells 

      Stanczak, Michal A; Siddiqui, Shoib S; Trefny, Marcel P; Thommen, Daniela S; Boligan, Kayluz Frias; von Gunten, Stephan; Tzankov, Alexandar; Tietze, Lothar; Lardinois, Didier; Heinzelmann-Schwarz, Viola; von Bergwelt-Baildon, Michael; Zhang, Wu; Lenz, Heinz-Josef; Han, Younghun; Amos, Christopher I; Syedbasha, Mohammedyaseen; Egli, Adrian; Stenner, Frank; Speiser, Daniel E; Varki, Ajit; Zippelius, Alfred; Läubli, Heinz (2018-11-01)
      First-generation immune checkpoint inhibitors, including anti-CTLA-4 and anti-programmed death 1 (anti-PD-1) antibodies, have led to major clinical progress, yet resistance frequently leads to treatment failure. Thus, new ...