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Using serum CA125 to assess the activity of potential cytostatic agents in ovarian cancer
(2014-05)
Objective: New strategies are required to rapidly identify novel cytostatic agents before embarking on large randomized trials. This study investigates whether a change in rate of rise (slope) of serum CA125 from before ...
Detection of disease change from a biological marker : using CA125 in ovarian cancer as an example
(2012)
Objectives: In Oncology drug development, the great majority of phase 3 trials are negative. New strategies are required to rapidly identify novel agents prior to large randomised trials. The CA125 doubling trial successfully ...
Detection of disease change using a biological marker and clinical application: CA125 in ovarian cancer patients
(2012)
In Oncology drug development, the great majority of phase 3 trials are negative.. New strategies are required to rapidly identify novel agents prior to large randomised trials. The CA125 doubling trial successfully showed ...