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Dendritic Morphology Predicts Pattern Recognition Performance in Multi-compartmental Model Neurons with and without Active Conductances
(2015-04-01)
In this paper we examine how a neuron’s dendritic morphology can affect its pattern recognition performance. We use two different algorithms to systematically explore the space of dendritic morphologies: an algorithm that ...
Multiplicative gain modulation arising from inhibitory synaptic plasticity in the cerebellar nuclei
(2014)
Neurons use the rate of action potentials to encode sensory variables. This makes the output rate as a function of input, also known as input-output (I–O) relationship, a core computational function in neuronal processing. ...
Synaptic plasticity and pattern recognition in cerebellar Purkinje cells
(Springer Nature, 2014)
Many theories of cerebellar learning assume that long-term depression (LTD) of synapses between parallel fibres (PFs) and Purkinje cells is the basis for pattern recognition in the cerebellum. Here we describe a series of ...
Short-term depression of inhibitory Purkinje cell synapses enhances gain modulation in the cerebellar nuclei
(2013-07)
Poster presented at CNS 2013
Evolution of Dendritic Morphologies Using Deterministic and Nondeterministic Genotype to Phenotype Mapping
(Springer Nature, 2013)
In this study, two morphological representations in the genotype, a deterministic and a nondeterministic representation, are compared when evolving a neuronal morphology for a pattern recognition task. The deterministic ...
Characterising the performance of balanced memory networks
(2013)
Poster presented at CNS 2013
A potential role for the cerebellar nuclei in absence seizures
(2013)
Poster presented ar CNS 2013
Determinants of associative memory performance in spiking and non-spiking neural networks with different synaptic plasticity regimes
(2012)
Poster presented at CNS 2012
STD-dependent and independent encoding of input irregularity as spike rate in a computational model of a cerebellar nucleus neuron
(2011)
Neurons in the cerebellar nuclei (CN) receive inhibitory inputs from Purkinje cells in the cerebellar cortex and provide the major output from the cerebellum, but their computational function is not well understood. It has ...
The Beneficial Effects of Non-specific Synaptic Plasticity for Pattern Recognition in Auto-associative Memory
(2011)
Poster presented at CNS 2011