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Flunixin pharmacokinetics and serum thromboxane inhibition in the dog
(1989)
Flunixin meglumine administered orally to beagle dogs at doses of 0.55, 1.10 or 1.65 mg/kg bodyweight was rapidly absorbed to produce maximum mean plasma concentrations of 2.40 +/- 0.70, 4.57 +/- 1.12 and 7.42 +/- 2.07 ...
Relay bioavailability and toxicity of isometamidium residues : a model for human risk assessment
(1989)
The bioavailability and potential toxicity of the residues of the antitrypanosomal drug isometamidium (ISMM) in bovine tissues were investigated in male Sprague-Dawley rats. They were allowed to feed for 7 and 21 days on ...
The pharmacodynamics of ivermectin in sheep and cattle
(1988-09)
The concentrations of ivermectin in the gastrointestinal tract of sheep and cattle were determined after subcutaneous administration of ivermectin. Ivermectin was not detected (limit of detection 1 ng/ml) in abomasal and ...
Production of strains of the sheep parasite Ostertagia circumcincta by implantation of adult parasites into the abomasum of lambs
(1988-07)
The implantation of a single pair of adult parasites of Ostertagia circumcincta via the abomasa of four lambs resulted in the production of 19, 53, 393 and 425 viable larvae after faecal culture using faeces collected from ...
Efficacy of ivermectin against Cooperia curticei infection in sheep
(1988)
Lambs were inoculated with a single dose of Cooperia curticei. Subcutaneous administration of ivermectin at a dosage of 200 micrograms/kg of body weight resulted in 61.1% and 90.4% anthelmintic efficacy, when measured at ...
Penicillin therapy of spontaneous streptococcal meningitis in pigs
(1987-10)
Oral prophylactic medication with either procaine penicillin G or a mixture of chlortetracycline, sulphadimidine and procaine penicillin G reduced the incidence of streptococcal meningitis in a herd of pigs with a high ...
Effect of sodium cromoglycate on the response to Ostertagia circumcincta in adult sheep
(1987-09)
Serum pepsinogen concentrations rose more rapidly and to higher levels in adult sheep infected with Ostertagia circumcincta and treated orally with the mast cell stabilising agent sodium cromoglycate than they did in adult ...