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Antimicrobial resistance: a veterinary perspective
(1998-09-05)
Bacterial disease is a major constraint on the efficient production of animal derived food and causes ill health and suffering in both food producing and companion animals. In some production systems the spread of bacterial ...
Measurement of cyclooxygenase inhibition in vivo : a study of two non-steroidal anti-inflammatory drugs in sheep
(1998-08)
The anti-inflammatory effects of the non-steroidal anti-inflammatory drugs phenylbutazone (PBZ) and flunixin meglumine (FM) and the relationship between the effects and drug concentration in vivo were studied using a ...
The processes influencing the distribution of parasitic nematodes among naturally infected lambs
(1998-08)
The impact of mixed, nematode infection upon a group of animals will depend upon the number of nematodes present, how they are distributed among hosts and whether individuals that are heavily parasitized with one species ...
Pharmacokinetic studies of flunixin meglumine and phenylbutazone in plasma, exudate and transudate in sheep
(1998-08)
Flunixin meglumine (FM, 1.1 mg/kg) and phenylbutazone (PBZ, 4.4 mg/kg) were administered intravenously (i.v.) as a single dose to eight sheep prepared with subcutaneous (s.c.) tissue-cages in which an acute inflammatory ...
Changes in the zymogenic cell populations of the abomasa of sheep infected with Haemonchus contortus
(1998-06)
The effects of dietary urea supplementation and of a 10-week trickle infection regime, simulating chronic exposure to Haemonchus contortus, on the zymogenic population of the abomasa of Hampshire Down lambs was examined, ...
Pharmacodynamics and pharmacokinetics of tolfenamicacid in ruminating calves: Evaluation in models of acute inflammation
(1998-05)
Injections of mild irritants intradermally (carrageenan, zymosan and dextran) and intracaveally (carrageenan)in a tissue cage model of inflammation were used in studies of the pharmacodynamics and pharmacokinetics of ...
Pharmaceutical quality of anthelmintics sold in Kenya
(1998-04)
Nine anthelmintic products purchased in pharmacies and from agricultural merchants in Kenya were tested for pharmaceutical quality. The concentration of active drug was compared with the claim on the label, and the variability ...
Comparative field evaluation of divided-dosing and reduced feed intake upon treatment efficacy against resistant isolates of Teladorsagia circumcincta in sheep and goats
(1998-03)
The effects of modifying drug administration and food intake upon the efficacy of fenbendazole against resistant isolates of Teladorsagia (Ostertagia) circumcincta were investigated using naturally infected sheep and goats. ...
Pharmacokinetics and tissue disposition of danofloxacin in sheep
(1998-03)
The plasma pharmacokinetics of danofloxacin administered at 1.25 mg kg(-1) body weight by the intravenous and intramuscular routes were determined in sheep. Tissue distribution was also determined following administration ...
The effects of excretions/secretions of Ostertagia circumcincta on ovine abomasal tissues in vitro
(1998-03)
Products excreted/secreted by Ostertagia circumcincta stimulated the in vitro release of pepsinogen from intact abomasal mucosal sheets and caused the contraction of strips of abomasal smooth muscle, also in vitro. However, ...