Now showing items 1-10 of 78
The reaction of flavonoid metabolites with peroxynitrite
There is much interest in the bioactivity of in vivo flavonoid metabolites. We report for the first time the hierarchy of reactivity of flavonoid metabolites with peroxynitrite and characterise novel reaction products. ...
Exploitation of immunofluorescence for the quantification and characterization of small numbers of Pasteuria endospores
The Pasteuria group of endospore-forming bacteria has been studied as a biocontrol agent of plant-parasitic nematodes. Techniques have been developed for its detection and quantification in soil samples, and these mainly ...
An investigation into the in vivo performance variability of pH responsive polymers for ileo-colonic drug delivery using gamma scintigraphy in humans
Gastrointestinal performance of tablets coated with pH responsive acrylic polymers (Eudragit) was investigated in human volunteers. Tablet cores were coated with Eudragit S dissolved in ethanol (organic), Eudragit S aqueous ...
Absorption of the nerve agent VX (O-ethyl-S-[2(di-isopropylamino)ethyl] methyl phosphonothioate) through pig, human and guinea pig skin in vitro
The physico-chemical properties of VX make the skin the most likely route of absorption into the human body. The development of effective medical countermeasures against such percutaneous threat agents relies on the use ...
Psychotherapists’ theoretical orientations as elaborative choices.
(John Wiley & Sons, 2006-12)
Occurrence and variability of Potato yellow vein virus in three departments of Colombia
Potato yellow vein virus (PYVV) causes dramatic yield reductions in potatoes in Andean countries, particularly Colombia. We tested 250 potato leaf samples suspectedly infected with PYVV from three Colombian Departments and ...
In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates, the selective 5-hydroxytryptamine 1a agonist (R)-(+)-8-OHDPAT inhibits levodopa-induced dyskinesia but only with\increased motor disability
5-Hydroxytryptamine 1a (5-HT1a) receptor agonists, such as sarizotan and tandospirone, are reported to reduce levodopainduced dyskinesia in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaques and in ...
Systematic review of medication errors in pediatric patients
To systematically locate and review studies that have investigated the incidence of medication errors (MEs) in pediatric inpatients and identify common errors.
Evidence for flocculation-controlled microcrystallisation of salmeterol xinafoate
The therapeutic management of pulmonary disease depends upon the efficient delivery of aerosolized drug particles with an aerodynamic diameter of 2.5–6 mm (Pritchard 2001). Particles for such aerosols are routinely produced ...
Determination of the diffusion coefficient of cyanophenol in carbosil membrane using ATR-FTIR spectroscopy
Model membranes are often used in place of human skin when evaluating dermal drug delivery systems. This is because they offer several advantages compared with human epidermis including their ready availability, uniformity ...