Now showing items 11-20 of 123
Synthesis of genomic and subgenomic RNAs by a membrane-bound RNA-dependent RNA polymerase isolated from oat plants infected with cereal yellow dwarf virus
A membrane-bound RNA-dependent RNA polymerase (RdRp) complex was isolated by differential sedimentation from oat plants infected with cereal yellow dwarf virus (CYDV). When incubated with P-32-labelled UTP, unlabelled ATP, ...
Systematic review of medication errors in pediatric patients
To systematically locate and review studies that have investigated the incidence of medication errors (MEs) in pediatric inpatients and identify common errors.
Molecular characterization of the largest mycoviral-like double-stranded RNAs associated with Amasya cherry disease, a disease of presumed fungal aetiology
The sequence of the four large Q double-stranded RNAs (dsRNAs) associated with Amasya cherry disease (ACD), which has a presumed fungal aetiology, is reported. ACID L dsRNAs 1 (5121 bp) and 2 (5047 bp) potentially encode ...
Stabilisation of deoxyribonuclease in hydrofluoroalkanes using miscible vinyl polymers
A mix of biocompatible macromolecules (poly(vinyl alcohol) (PVA) and poly(vinyl pyrrolidone) (PVP)) has been shown previously to enhance the physical stability of non-aqueous pharmaceutical suspensions. The aim of this ...
Determination of the diffusion coefficient of cyanophenol in carbosil membrane using ATR-FTIR spectroscopy
Model membranes are often used in place of human skin when evaluating dermal drug delivery systems. This is because they offer several advantages compared with human epidermis including their ready availability, uniformity ...
Evidence for flocculation-controlled microcrystallisation of salmeterol xinafoate
The therapeutic management of pulmonary disease depends upon the efficient delivery of aerosolized drug particles with an aerodynamic diameter of 2.5–6 mm (Pritchard 2001). Particles for such aerosols are routinely produced ...
Matrix changes induced by transglutaminase 2 lead to inhibition of angiogenesis and tumor growth
Administration of active TG2 to two different in vitro angiogenesis assays resulted in the accumulation of a complex extracellular matrix (ECM) leading to the suppression of endothelial tube formation without causing cell ...
Distinct epidermal stem cell compartments are maintained by independent niche microenvironments
The mammalian epidermis is a stratified, multilayered epithelium, consisting of the interfollicular epidermis and associated appendages, which extend into the dermis and include hair follicles, sebaceous glands, and sweat ...