Now showing items 51-60 of 356
Direct metabolic fingerprinting of commercial herbal tinctures by nuclear magnetic resonance spectroscopy and mass spectrometry
Tinctures are widely used liquid pharmaceutical preparations traditionally obtained by maceration of one or more medicinal plants in ethanol-water solutions. Such a process results in the extraction of virtually hundreds ...
Reaching the journey’s end : Reflections on the final phase of a problem-based learning group
This paper represents the final phase of a journey within a self-directed problem-based learning group occurring on the Doctorate in Clinical Psychology Programme based at the University of Hertfordshire. It provides ...
Insecticide and acaricide resistance
(Academic Press, 2009)
Improvement in the transition of a student from secondary or further education into science higher education : Is there a mismatch between staff and students' expectations as to what is required to study science?
The aim this project is to consider if we can improve the transition of a student from secondary or further education into science higher education by analysing whether there is a mismatch between staff and students’ ...
Quantitative particle size, microtextural and outline shape analyses of glacigenic sediment reworked by paraglacial debris flows
Particle size analysis and scanning electron microscopy have been used with some success to differentiate sediments sampled from varying geomorphological environments. In the paraglacial environment, however, discrimination ...
Hedgehog Signalling in Androgen Independent Prostate Cancer
Objectives: Androgen-deprivation therapy effectively shrinks hormone-naïve prostate cancer, both in the prostate and at sites of distant metastasis. However prolonged androgen deprivation generally results in relapse and ...
The Effect of Phenyl Substituents on C-13 NMR Shifts and Metal Ions Binding to 4-Phenyl-2,4-Dioxobutanoic Acid Derivatives
Butanoic moiety of 4-aryl-2,4-dioxobutanoic acids is involved in interactions with metal ions within HIV-1 integrase active site. Sixteen congeneric 4-phenyl-2,4-dioxobutanoic acid derivatives with different substitution ...
Investigations into the formulation of metered dose inhalers of salmeterol xinafoate and fluticasone propionate microcrystals
Purpose. To investigate the aerosolization and behaviour of microparticles of salmeterol xinafoate (SX) and fluticasone propionate (FP) suspended in hydrofluoroalkane (HFA) propellant. Methods. Microcrystals of SX and FP ...
Reliability of human cryopreserved hepatocytes and liver microsomes as in vitro systems to predict metabolic clearance
A total of 110 drugs, selected to cover a range of physicochemical and pharmacokinetic properties, were used to explore standard approaches to the prediction of in vivo metabolic clearance using drug-depletion profiles ...