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Determination of short-chain fatty acids in equine caecal liquor by ion exchange high performance liquid chromatography after solid phase extraction
(1991-09)
A high performance liquid chromatography (HPLC) method was developed for the determination of seven short-chain fatty acids in equine caecal liquor. Samples were cleaned up on a Sep-pak (C18) cartridge, and the analyte was ...
Pharmacokinetic, biochemical and tolerance studies on carprofen in the horse
(1991-07)
Carprofen, a non-steroidal anti-inflammatory drug (NSAID) was administered to three Thoroughbred geldings and three Shetland ponies to determine its plasma disposition and tolerance. The main pharmacokinetic characteristics ...
Effect of parasitism with Nematodirus battus on the pharmacokinetics of levamisole, ivermectin and netobimin
(1991-07)
The pharmacokinetics of levamisole, ivermectin and netobimin administered orally and by subcutaneous injection were compared in lambs exposed to a moderate challenge with Nematodirus battus and in parasite naive lambs. ...
The pharmacology of flukicidal drugs
(1991-07)
Pharmacokinetics and pharmacodynamics of piroxicam in dogs
(1991-06)
Piroxicam was administered to beagle dogs intravenously and orally at a dose rate of 0.3 mg/kg bodyweight. It had an elimination half-life of 40.2 hours, a volume of distribution of 0.29 +/- 0.02 litres/kg and a body ...
Pharmacokinetics and clinical efficacy of a cinchophen and prednisolone combination in the dog
(1991-02)
The kinetics and efficacy of a cinchophen prednisolone combination preparation (PLT) were assessed in the dog. Cinchophen administered at a dose rate of 12-5 mg/kg intravenously had a volume of distribution (Vd area) of ...
Isometamidium in pigs : disposition kinetics, tissue residues and adverse reactions
(1991-01)
The disposition and adverse effects of the anti-trypanosomal drug isometamidium in pigs were evaluated. Following intramuscular administration of the drug at doses of 0.5, 15 and 35 mg kg-1, the drug was rapidly absorbed ...