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Effects of a novel lanosterol 14α-demethylase inhibitor on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in Hep G2 cells
A 32-carboxylic acid derivative of lanosterol (SKF 104976) was found to be a potent inhibitor of lanosterol 14α-demethylase (14αDM). 14αDM activity in a Hep G2 cell extract was inhibited 50% by 2 nM SKF 104976. Exposure ...
Effects of fungicides on eyespot in five successive crops of winter wheat in plots with different initial or fungicide-selected populations of Pseudocercosporella herpotrichoides
The effects on eyespot of carbendazim, prochloraz or a mixture of carbendazim and prochloraz, applied twice yearly and to the same plots in each year, were studied in five successive crops of winter wheat. Some plots were ...
The biology of Mycosphaerella capsellae sp. nov., the teleomorph of Pseudocercosporella capsellae, cause of white leaf spot of oilseed rape
Mycosphaerella capsellae sp. nov. is reported as the teleomorph of Pseudocercosporella capsellae, the cause of white leaf spot on oilseed rape and other crucifers. Spermogonia and protoascomata were observed in white leaf ...
The development of eyespot on stems of winter wheat and winter barley in crops inoculated with W-type or R-type isolates of Pseudocercosporella herpotrichoides
In three contrasting seasons (1986-1988), W-type isolates of Pseudocercosporella herpotrichoides generally became established on stems of winter wheat or winter barley plants more rapidly than did R-type isolates. After ...
Status of diseases of linseed in the U.K
Linseed is a rapidly expanding crop in the UK, with an area fast approaching 120,000 ha, making the UK the biggest producer of linseed in Europe. A range of 15 pathogens, with the potential to cause disease problems in the ...
Determination of short-chain fatty acids in equine caecal liquor by ion exchange high performance liquid chromatography after solid phase extraction
A high performance liquid chromatography (HPLC) method was developed for the determination of seven short-chain fatty acids in equine caecal liquor. Samples were cleaned up on a Sep-pak (C18) cartridge, and the analyte was ...
The complete nucleotide sequence of tobacco necrosis virus strain D
The complete sequence of the RNA genome of tobacco necrosis virus strain D (TNV-D) consisting of 3759 nucleotides has been determined. The positive strand contains five open reading frames (ORFs). The 5'proximal ORF encodes ...
Effect of parasitism with Nematodirus battus on the pharmacokinetics of levamisole, ivermectin and netobimin
The pharmacokinetics of levamisole, ivermectin and netobimin administered orally and by subcutaneous injection were compared in lambs exposed to a moderate challenge with Nematodirus battus and in parasite naive lambs. ...
The nucleotide sequence of the infectious cloned DNA components of potato yellow mosaic virus
The complete nucleotide sequence of a Venezuelan isolate of potato yellow mosaic virus (PYMV) has been determined, showing it to be typical of subgroup I geminiviruses in that it is whitefly-transmitted, has a circular, ...
The pharmacology of flukicidal drugs