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Anti-CTLA-4 (CD 152) monoclonal antibody-induced autoimmune interstitial nephritis
(2009-04-28)
Targeted immune-modulating agents are entering clinical practice in many specialties, providing novel therapeutic possibilities but introducing new potential toxicities. We present the first reported case, to our knowledge, ...
Residual renal function improves outcome in incremental haemodialysis despite reduced dialysis dose
(2009-02-24)
Background and Methods. The importance of residual renal function is well recognized in peritoneal dialysis but its role in haemodialysis (HD) has received much less attention. We studied 650 incident patients in our ...
The Pan-Thames EPS study : treatment and outcomes of encapsulating peritoneal sclerosis
(2009)
Background: Encapsulating peritoneal sclerosis (EPS) is a disease process that can occur as a complication of peritoneal dialysis (PD). The aim of this study was to make a general assessment of the clinical features, ...
Are low erythropoietin and 1,25-dihydroxyvitamin D levels indicative of tubulo-interstitial dysfunction in diabetes without persistent microalbuminuria?
(2009)
Aims: To investigate the relationship between Erythropoietin (EPO) and 1,25-dihydroxyvitamin D levels, and tubular damage in patients with diabetes mellitus (DM) without persistent microalbuminuria. Methods: We measured ...
Erythropoietic stress and anemia in diabetes mellitus
(2009)
Anemia is one of the world's most common preventable conditions, yet it is often overlooked, especially in people with diabetes mellitus. Diabetes-related chronic hyperglycemia can lead to a hypoxic environment in the renal ...
“Benign” hypergammaglobulinemic purpura is not benign in pregnancy
(2009)
A woman presented at 25 weeks gestation in her first pregnancy with severe preeclampsia and an intrauterine death. It later emerged that she had Waldenstrom’s benign hypergammaglobulinemic purpura. We discuss the implications ...
UK Renal Registry 11th Annual Report : Chapter 4 ESRD prevalent rates in 2007 in the UK : national and centre-specific analyses
(2009)
Introduction: This chapter describes the demographics of UK RRT patients in 2007. Methods: Complete data were electronically collected from 71 UK centres with the remaining 1 centre submitting summary data. A series of ...
Molecularly imprinted sol gel for ibuprofen : an analytical study of the factors influencing selectivity
(2009)
This paper describes the preparation and testing of a sol gel specific for the non-steroidal anti-inflammatory drug ibuprofen. Ibuprofen was selected as a model compound due to the fact that it contains a number of structural ...
UK Renal Registry 11th Annual Report : Chapter 3 : ESRD incident rates in 2007 in the UK : national and centre-specific analyses.
(2009)
Introduction: This chapter describes the characteristics of adult patients starting renal replacement therapy (RRT) in the UK in 2007 and the acceptance rate for RRT in Primary Care Trusts (PCT) or equivalent Health Authority ...
Long-Term Outcomes in Online Hemodiafiltration and High-Flux Hemodialysis : A Comparative Analysis
(2009)
Background and objectives: Theoretical advantages exist of online hemodiafiltration (HDF) over high-flux hemodialysis (HD), but outcome data are scarce. Our objective was to compare outcomes between these modalities. Design, ...