Now showing items 1-10 of 16
The reaction of flavonoid metabolites with peroxynitrite
There is much interest in the bioactivity of in vivo flavonoid metabolites. We report for the first time the hierarchy of reactivity of flavonoid metabolites with peroxynitrite and characterise novel reaction products. ...
Exploitation of immunofluorescence for the quantification and characterization of small numbers of Pasteuria endospores
The Pasteuria group of endospore-forming bacteria has been studied as a biocontrol agent of plant-parasitic nematodes. Techniques have been developed for its detection and quantification in soil samples, and these mainly ...
Occurrence and variability of Potato yellow vein virus in three departments of Colombia
Potato yellow vein virus (PYVV) causes dramatic yield reductions in potatoes in Andean countries, particularly Colombia. We tested 250 potato leaf samples suspectedly infected with PYVV from three Colombian Departments and ...
Absorption of the nerve agent VX (O-ethyl-S-[2(di-isopropylamino)ethyl] methyl phosphonothioate) through pig, human and guinea pig skin in vitro
The physico-chemical properties of VX make the skin the most likely route of absorption into the human body. The development of effective medical countermeasures against such percutaneous threat agents relies on the use ...
Sequence of RNA-dependent RNA polymerase genes provides evidence for three more distinct mitoviruses in Ophiostoma novo-ulmi isolate Ld
Three of the twelve double-stranded (ds) RNAs, dsRNAs 1a, 1b and 3b, which are located in the mitochondria of a diseased isolate, Ld, of the Dutch elm disease fungus, Ophiostoma novo-ulmi have been cDNA cloned and sequenced. ...
Postgraduate education for advanced practitioners : a novel approach to course design
Describes a new approach to developing learning to support advanced practitioner development which builds on the positive experiences of how adults learn, education theory, clinical practice and peer review
NK1 antagonists based on seven membered lactam scaffolds
A new class of high affinity hNK(1)R antagonists based on seven-membered ring cores has been identified. This series, with relatively simple, compact structures, includes compounds with high affinity, good selectivity, and ...
Resistance to Leptosphaeria maculans (phoma stem canker) in Brassica napus (oilseed rape) induced by Leptosphaeria biglobosa and chemical defence activators in field and controlled environments
Effects of pretreatment of Brassica napus leaves with ascospores of Leptosphaeria biglobosa or chemical defence activators [acibenzolar-S-methyl (ASM) or menadione sodium bisulphite (MSB)] on infection by ascospores of ...
MPTP treatment of common marmosets impairs proteasomal enzyme activity and decreases expression of structural and regulatory elements of the 26S proteasome
Dysfunction of the ubiquitin-proteasome system occurs in the substantia nigra (SN) in Parkinson's disease (PD). However, it is unknown whether this is a primary cause or a secondary consequence of other components of the ...
Using multi-environment sugar beet variety trials to screen for drought tolerance
Drought is a major limitation to sugar beet yield in many rainfed areas. Varieties with increased drought tolerance would improve productivity, but breeding specifically for drought tolerance is time-consuming and expensive. ...