Now showing items 1-10 of 122
Exploitation of immunofluorescence for the quantification and characterization of small numbers of Pasteuria endospores
The Pasteuria group of endospore-forming bacteria has been studied as a biocontrol agent of plant-parasitic nematodes. Techniques have been developed for its detection and quantification in soil samples, and these mainly ...
In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates, the selective 5-hydroxytryptamine 1a agonist (R)-(+)-8-OHDPAT inhibits levodopa-induced dyskinesia but only with\increased motor disability
5-Hydroxytryptamine 1a (5-HT1a) receptor agonists, such as sarizotan and tandospirone, are reported to reduce levodopainduced dyskinesia in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaques and in ...
Absorption of the nerve agent VX (O-ethyl-S-[2(di-isopropylamino)ethyl] methyl phosphonothioate) through pig, human and guinea pig skin in vitro
The physico-chemical properties of VX make the skin the most likely route of absorption into the human body. The development of effective medical countermeasures against such percutaneous threat agents relies on the use ...
An investigation into the in vivo performance variability of pH responsive polymers for ileo-colonic drug delivery using gamma scintigraphy in humans
Gastrointestinal performance of tablets coated with pH responsive acrylic polymers (Eudragit) was investigated in human volunteers. Tablet cores were coated with Eudragit S dissolved in ethanol (organic), Eudragit S aqueous ...
The reaction of flavonoid metabolites with peroxynitrite
There is much interest in the bioactivity of in vivo flavonoid metabolites. We report for the first time the hierarchy of reactivity of flavonoid metabolites with peroxynitrite and characterise novel reaction products. ...
Occurrence and variability of Potato yellow vein virus in three departments of Colombia
Potato yellow vein virus (PYVV) causes dramatic yield reductions in potatoes in Andean countries, particularly Colombia. We tested 250 potato leaf samples suspectedly infected with PYVV from three Colombian Departments and ...
Development and uptake of a scheme for predicting risk of severe light leaf spot on oilseed rape
To reduce reliance on fungicides for disease control on oilseed rape, Decision Support Systems (DSS) are being developed to guide fungicide applications as part of an integrated pest and disease management strategy. This ...
Psychotherapists’ theoretical orientations as elaborative choices.
(John Wiley & Sons, 2006-12)
Amanicadol, a pimarane-type diterpene from Phlomis amanica Vierch
Fractionation of the methanol extract of Phlomis amanica resulted in the isolation of a new pimarane type diterpene, amanicadol (1), together with the known glycosides lamiide, verbascoside (= acteoside), syringaresinol-4-O-β- ...
In vitro synthesis of minus-strand RNA by an isolated cereal yellow dwarf virus RNA-dependent RNA polymerase requires VPg and a stem-loop structure at the 3' end of the virus RNA
Cereal yellow dwarf virus (CYDV) RNA has a 5'-terminal genome-linked protein (VPg). We have expressed the VPg region of the CYDV genome in bacteria and used the purified protein (bVPg) to raise an antiserum which was able ...