Browsing Research publications by Author "Lunt, Mark"
Now showing items 1-3 of 3
-
HLA-DRB1 Amino Acid Positions 11/13, 71, and 74 Are Associated With Inflammation Level, Disease Activity, and the Health Assessment Questionnaire Score in Patients With Inflammatory Polyarthritis
Ling, Stephanie F; Viatte, Sebastien; Lunt, Mark; Van Sijl, Alper M; Silva-Fernandez, Lucia; Symmons, Deborah P M; Young, Adam; Macgregor, Alexander J; Barton, Anne (2016-06-06)OBJECTIVE: Rheumatoid arthritis (RA) susceptibility HLA-DRB1 haplotypes based on amino acid positions 11/13, 71, and 74 predict radiographic damage. The mechanism of action is unknown, but it may be mediated by inflammation. ... -
Influence of Social Support, Financial Status, and Lifestyle on the Disparity Between Inflammation and Disability in Rheumatoid Arthritis
Gwinnutt, James M.; Norton, Sam; Hyrich, Kimme L.; Lunt, Mark; Combe, Bernard; Rincheval, Nathalie; Ruyssen‐Witrand, Adeline; Fautrel, Bruno; McWilliams, Daniel F.; Walsh, David A.; Nikiphorou, Elena; Kiely, Patrick D. W.; Young, Adam; Chipping, Jacqueline R.; MacGregor, Alex; Verstappen, Suzanne M. M. (2023-04-24)Objective: To investigate how social support, financial status, and lifestyle influence the development of excess disability in rheumatoid arthritis (RA). Methods: Data were obtained from the Étude et Suivi des Polyarthrites ... -
Not all moderate disease is the same - Identification of disability trajectories among patients with rheumatoid arthritis and moderate disease activity
Pan, Yi; Norton, Sam; Gwinnutt, James M.; Kearsley-Fleet, Lianne; Symmons, Deborah P.M.; Lunt, Mark; Young, Adam; Hyrich, Kimme L.; Verstappen, Suzanne M.M. (2019-05-20)BACKGROUND: United Kingdom guidelines for the use of biologic disease modifying anti-rheumatic drugs (bDMARDS) for rheumatoid arthritis (RA) require patients to have active disease (Disease Activity Score [DAS28] >5.1) and ...