Browsing Research publications by Author "O'Leary, Valerie"
Now showing items 1-2 of 2
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A Defined Heteromeric KV1 Channel Stabilizes the Intrinsic Pacemaking and Regulates the Efferent Code of Deep Cerebellar Nuclear Neurons to Thalamic Targets
Ovsepian, Saak; Steuber, Volker; Le Berre, Marie; O'Hara, Liam; O'Leary, Valerie; Dolly, Oliver (2013-04)The output of the cerebellum to the motor axis of the central nervous system is orchestrated mainly by synaptic inputs and intrinsic pacemaker activity of deep cerebellar nuclear (DCN) projection neurons. Herein, we ... -
Distinctive Role of KV1.1 Subunits in the Biology and Functions of Low Threshold K+ Channels with Implication for Neurological Disease
Ovsepian, Saak; Le Berre, Marie; Steuber, Volker; O'Leary, Valerie; Leibold, Christian; Dolly, Oliver (2016-03-01)The diversity of pore-forming subunits of KV1 channels (KV1.1–KV1.8) affords their physiological versatility and predicts a range of functional impairments resulting from genetic aberrations. Curiously, identified so far ...