Now showing items 1-3 of 3
Poly-glutamic dendrimer-based conjugates for cancer vaccination - a computational design for targeted delivery of antigens
Computational techniques are useful to predict interaction models and molecular properties for the design of drug delivery systems, such as dendrimers. Dendrimers are hyperbranched macromolecules with repetitive building ...
Optimization of protein loaded PLGA nanoparticles manufacturing parameters following a quality-by-design approach
Development of a multivariate-based regression model for estimating the critical attributes for establishing a design-space for poly(lactic-co-glycolic acid) (PLGA) nanoparticles formulated by a double emulsion-solvent ...
From sequence to 3D structure of hyperbranched molecules : application to surface modified PAMAM dendrimers
The molecular modeling of hyperbranched molecules is currently constrained by difficulties in model building, due partly to lack of parameterization of their building blocks. We have addressed this problem with specific ...