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A simple formulation of microtubule dynamics: quantitative implications of the dynamic instability of microtubule
A simple formulation of microtubule dynamic instability is presented, which is based on the experimental observations by T. Horio and H. Hotani of coexisting, interconverting growing and shrinking microtubules. Employing ...
A Lateral Cap model of microtubule dynamic instability
The co-existence and interconversion of growing and shrinking microtubules have been termed ‘dynamic instability’, and have been directly observed to occur under a variety of conditions in vitro and in vivo. Previous ...
HARP: A Parallel Pipelined RISC Processor
HARP (the Hatfield RISC processor) is a reduced instruction set processor being developed at Hatfield Polytechnic, UK. The major aim of the HARP project is to develop a RISC processor capable of a sustained instruction ...
The positive fixed points of Banach lattices
Let Z be a Banach lattice endowed with positive cone C and an order-continuous norm j.j . Let G be a left-amenable semigroup of positive linear endomorphisms of Z . Then the positive fixed points Co of Z under G form a ...
The effect of podophyllotoxin on microtubule dynamics
We have investigated the effects of podophyllotoxin on the dynamic properties of microtubules assembled from pure tubulin dimer. Excess podophyllotoxin causes the complete disassembly of microtubules, through formation of ...