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Hypoactivation and Dysconnectivity of a Frontostriatal Circuit During Goal-Directed Planning as an Endophenotype for Obsessive-Compulsive Disorder
(2017-11-01)
Background The symptoms of obsessive-compulsive disorder (OCD) have been postulated to result from impaired executive functioning and excessive habit formation at the expense of goal-directed control and have been objectively ...
Academics at the intersection of age and gender: : A Ghanaian experience
(Routledge, 2017-08-25)
High Prevalence of Neuropathic Pain Component in Patients with Low Back Pain : Evidence from Meta-Analysis
(2017-07-01)
BACKGROUND: Low back pain (LBP) is a complex syndrome which includes a nociceptive (NcP) component, a neuropathic (NeP) component, or a mixture of components (mixed pain). The NeP component (NePC) in LBP is defined as the ...
Specific Frontostriatal Circuits for Impaired Cognitive Flexibility and Goal-Directed Planning in Obsessive-Compulsive Disorder : Evidence From Resting-State Functional Connectivity
(2017-04-15)
Background A recent hypothesis has suggested that core deficits in goal-directed behavior in obsessive-compulsive disorder (OCD) are caused by impaired frontostriatal function. We tested this hypothesis in OCD patients and ...
Synthetic Cannabinoids : psychopharmacology, clinical aspects, and psy-chotic onset
(2017-04-13)
Synthetic Cannabinoids (SC) are the widest and most diffused class of Novel Psychoactive Substances. SC are chemically heterogeneous and structurally dissimilar from delta-9-tetrahydrocannabinol, being full agonists of the ...
An analysis of the value of multiple mentors in formalised elite coach mentoring programmes
(2017-04-04)
ABSTRACT Background: Within the context of sports coaching and coach education, formalised mentoring relationships are often depicted as a mentor– mentee dyad. Thus, mentoring within sports coaching is typically conceptualised ...
Time, timing, talking and training : findings from an exploratory action research study to improve quality of end of life care for minority ethnic kidney patients
(2017-02-16)
Background. With an ageing and increasingly diverse population at risk from rising levels of obesity, diabetes and cardiovascular disease, including kidney complications, there is a need to provide quality care at all ...
The 'not-so-strange' body in the mirror: : A principal components analysis of direct and mirror self-observation
(2017-01-04)
In this study we adopted a psychometric approach to examine how the body is subjectively experienced in a mirror. One hundred and twenty-four healthy participants viewed their body for five minutes directly or via a mirror, ...
Nitrates for the Management of Acute Heart Failure Syndromes, A Systematic Review
(2017-01-01)
Intravenous nitrates are widely used in the management of acute heart failure syndrome (AHFS) yet with lack of robust evidence to support their use. We therefore sought to analyze all randomized studies that evaluated the ...