Now showing items 1-10 of 27
Phosphorylation of Pak1 by the p35/Cdk5 Kinase Affects Neuronal Morphology
The small GTPase Rac and its effectors, the Pak1 and p35/Cdk5 kinases, have been assigned important roles in regulating cytoskeletal dynamics in neurons. Our previous work revealed that the neuronal p35/Cdk5 kinase associates ...
Food, Social Policy and the Environment : Towards a New Model
Food policy is high on the public policy agenda, but still suffers from a lack of overview and integration. The paper reviews examples of policy limitations where tighter and more explicit links could usefully be made ...
From hospital admission to discharge : An exploratory study to evaluate seamless care
Aim. To evaluate the effect of pharmaceutical care from admission, through a hospital stay and following discharge. Design. The study design was descriptive, using qualitative methods to compare intensive pharmaceutical ...
An in vitro investigation into the effect of glycosaminoglycans on the skin partitioning and deposition of NSAIDs
Recently, Solaraze gel (Bioglan, Herts, UK) a topical hyaluronan (HA)/dictofenac formulation for the treatment of actinic keratosis has received regulatory approval in the US, Canada and Europe for the treatment of actinic ...
Conformationally restricted indolopiperidine derivatives as potent CCR2B receptor antagonists
The preparation and biological evaluation of a series of indolopiperidine CCR2B receptor antagonists possessing a conformationally restricted C-5 linker chain in combination with a restricted piperidine ring are described. ...
Habituating pigs for in-pen, non-invasive biophysical skin analysis
The purpose of this study was to develop a method for habituating pigs (Sus scrofa domcstica, middle white strain) to enable non-invasive, biophysical measurements of dorsal skin to be obtained on a daily basis over a ...
The development of software to support planning conversion to organic agriculture
Planning is essential to the successful conversion of conventional to organic farming. Currently, advisors base planning on personal experience and expertise, historical and market data. The process can be time consuming ...
On-farm risk assessment of agricultural pesticides
Effects of environmental factors on development of Pyrenopeziza brassicae (light leaf spot) apothecia on oilseed rape debris
The development of Pyrenopeziza brassicae (light leaf spot) apothecia was studied on petiole debris from artificially infected oilseed rape leaves incubated at temperatures from 6 to 22 degreesC under different wetness ...