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Pharmacovigilance Signals of the Opioid Epidemic over 10 Years: Data Mining Methods in the Analysis of Pharmacovigilance Datasets Collecting Adverse Drug Reactions (ADRs) Reported to EudraVigilance (EV) and the FDA Adverse Event Reporting System (FAERS)
(2022-05-27)
In the past twenty years, the consumption of opioid medications has reached significant proportions, leading to a rise in drug misuse and abuse and increased opioid dependence and related fatalities. Thus, the purpose of ...
A Focus on Abuse/Misuse and Withdrawal Issues with Selective Serotonin Reuptake Inhibitors (SSRIs): Analysis of Both the European EMA and the US FAERS Pharmacovigilance Databases
(2022-05-01)
Despite increasing reports, antidepressant (AD) misuse and dependence remain underestimated issues, possibly due to limited epidemiological and pharmacovigilance evidence. Thus, here we aimed to determine available ...
Misuse of anticholinergic medications: a systematic review.
(2022-02-01)
(1) Background: Over the last decade, misuse and diversion of medications has appeared to be increasingly concerning phenomena, including a range of different molecules. As current knowledge on the abuse of centrally acting ...
Knowledge and Use of Novel Psychoactive Substances in Italy: a Survey-Based Study in the General Population
(2021-11-08)
In this study, we aimed to identify the current trend of novel psychoactive substance (NPS) consumption in Italy and the level of knowledge about NPS in the general population and to explore the presence of risk factors ...
Club Drugs and Psychiatric Sequelae: An Issue of Vulnerability and Previous Psychiatric History
(2021-06-29)
The pursuit of pleasure among clubbers and disco-goers often involves drug use. However, whether substance use may represent a relevant risk factor contributing to the development of psychiatric symptoms and of mental ...
New Psychoactive Substances and suicidality: a systematic review of the current literature.
(2021-06-06)
Background and Objectives: Over the past twenty years a large number of New Psychoactive Substances (NPS) has entered and modified the recreational drug scene. Their intake has been associated with health-related risks, ...
Focus on over-the-counter drugs’ misuse; a systematic review on antihistamines, cough medicines and decongestants
(2021-05-07)
Background: Over the past 20 years or so the drug misuse scenario has seen the emergence of both prescription-only and over-the-counter (OTC) medications being reported as ingested for recreational purposes. OTC drugs such ...
Focus on over-the-counter drugs’ misuse; a systematic review on antihistamines, cough medicines and decongestants
(2021-05-07)
Background: Over the past 20 years or so the drug misuse scenario has seen the emergence of both prescription-only and over-the-counter (OTC) medications being reported as ingested for recreational purposes. OTC drugs such ...
Focus on over-the-counter drugs’ misuse; a systematic review on antihistamines, cough medicines and decongestants
(2021-05-07)
Background: Over the past 20 years or so the drug misuse scenario has seen the emergence of both prescription-only and over-the-counter (OTC) medications being reported as ingested for recreational purposes. OTC drugs such ...
New Psychoactive Substances (NPS) and Serotonin Syndrome onset: a Systematic Review
(2021-05-01)
The use of several new psychoactive substances (NPS) has become very popular and is posing global health risks. Chemically and pharmacologically diverse molecules are constantly emerging and are presenting with a wide range ...