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Now showing items 11-19 of 19
Fibrinolysis in platelet thrombi
(2021-05-12)
The extent and duration of occlusive thrombus formation following an arterial atherothrombotic plaque disruption may be determined by the effectiveness of endogenous fibrinolysis. The determinants of endogenous fibrinolysis ...
Assessment of endogenous fibrinolysis in clinical using novel tests - Ready for clinical roll-out?
(2021-04-01)
The occurrence of thrombotic complications, which can result in excess mortality and morbidity, represent an imbalance between the pro-thrombotic and fibrinolytic equilibrium.The mainstay treatment of these complications ...
Thrombotic complications in 2,928 patients with COVID-19 treated in intensive care: a systematic review
(2021-04-01)
A prothrombotic state is reported with severe COVID-19 infection, which can manifest in venous and arterial thrombotic events. Coagulopathy is reflective of more severe disease and anticoagulant thromboprophylaxis is ...
Antithrombotic therapy in diabetes: Which, when, and for how long?
(2021-03-25)
Cardiovascular disease remains the main cause of mortality in individuals with diabetes mellitus (DM) and also results in significant morbidity. Premature and more aggressive atherosclerotic disease, coupled with an enhanced ...
Ethnic Difference of Thrombogenicity in Patients with Cardiovascular Disease: A Pandora Box to Explain Prognostic Differences
(2021-03-01)
Arterial and venous atherothrombotic events are finely regulated processes involving acomplex interplay between vulnerable blood, vulnerable vessel, and blood stasis.Vulnerable blood (‘thrombogenicity’) comprises complex ...
Precision treatment in ACS – role of assessing fibrinolysis
(2021-03-01)
Despite advancements in pharmacotherapy and interventional strategies, patients with acute coronary syndrome (ACS) remain at risk of recurrent thrombotic events. In addition to an enhanced tendency to thrombus formation, ...
Role, laboratory assessment and clinical relevance of fibrin, factor XIII and endogenous fibrinolysis in arterial and venous thrombosis
(2021-02-02)
Diseases such as myocardial infarction, ischaemic stroke, peripheral vascular disease and venous thromboembolism are major contributors to morbidity and mortality. Procoagulant, anticoagu-lant and fibrinolytic pathways are ...
Prevalence of Thrombotic Complications in ICU-Treated Patients With Coronavirus Disease 2019 Detected With Systematic CT Scanning
(2021-01-06)
Objective: Severe Coronavirus disease 2019 (COVID-19) is associated with an extensive pneumonitis, and frequent coagulopathy. We sought the true incidence of thrombotic complications in critically ill patients with severe ...